Theory And Experimental Study On SPleen Deficiency Syndrome By The Therapy Of Cong Xing Li Pi(CXLP)

Objective Rests on《Huangdi Neijing》records "the heart to live the blood, the blood lives the spleen" and《Nanjing》records "tonifying the mother-organ while treating a case of deficient" the theory, to be better, treats spleen deficiency Syndrome effectively, but adjusts the heart to govern the blood, namely from the psychological spleen treatment spleen deficiency Syndrome , the deepening understood that the traditional Chinese medicine "the heart lives the spleen" the theory, and further discusses "the heart lives the spleen" the theory connotation, the heart spleen related possible material base and the application value through the experimental study.Methods The Chinese medicine five lines of theories believed that the heart is the fire, the spleen is the earth, the fire raw soil, the heart spleen relates for the mother and child, the theory has discussed the mechanism which the heart spleen altogether moves. "tonifying the mother-organ while treating a case of deficient" , flows swiftly the preparation spleen deficiency Syndrome animal model using the senna leaf.1. Selects Kunming to plant mouse 72 (body weight 18±2 gram), was half and half female and male, was the object of study, the compatibility feeds 6 days later, stochastically extracts 12 as the blank control group, other 60 divide into the model group, the bushing group, to make up the spleen group, to pass stochastically winds the group, the heart spleen altogether to adjust the group, and dips with the senna leaf fills the stomach establishment spleen animal model. All experiment mouse free diet. 2. After makes the mold success, namely starts for the medicine, each group gives the corresponding medicine separately the thick decoctum. 3. examination target: For medicine 12 days later examines separately makes up anything that sets one's mind at ease, to make up the spleen medicine, to pass winds the medicine and the heart spleen altogether adjusts the medicine to spleen weakness model mouse's influence. Observes its ordinary circumstances (bowel movement character, body weight, the spleen index), the D- xylose examination, and the third dial (MDA).Results 1. makes up the spleen group, the bushing group, to pass winds the group, the heart spleen altogether to adjust the group and the model group compares, can improve spleen weakness mouse body weight, the spleen index obviously, its central spleen altogether adjusts the group effect obviously to surpass makes up the spleen group, the bushing group and passes winds the group, 2. makes up the spleen medicine, to make up anything that sets one's mind at ease, to pass winds the medicine, the heart spleen altogether to adjust the medicine to be able to enhance in effectively spleen weakness model mouse small intestine the D- xylose content, The heart spleen group altogether moves with the model group compares (P<0. 01). 3. makes up the spleen medicine, to make up anything that sets one's mind at ease, to pass winds the medicine, the heart spleen altogether to adjust the medicine to be able to enhance in effectively spleen weakness model mouse urine the MDA content, The heart spleen group altogether moves with the model group compares (P<0.01).Conclusions Makes up the spleen group, the bushing group, to pass winds the group, the heart spleen altogether to adjust the group and the model group compares, can improve spleen weakness mouse body weight, the spleen index, the mouse small intestine D- xylose content and the spleen MDA content, its central spleen altogether adjusts the group effect obviously to surpass makes up the spleen group, the bushing group and passes winds the group. Therefore, the heart spleen altogether accent can be better, treats spleen weakness card effectively, its possible mechanism to manifest in: The heart for positive dirty (said that fire dirty), heart positive warm, helps the spleen to transport; The heart lives the blood, pent-up anger communizes, melts the blood principle spleen; The heart good blood, the heart positive passes warm, adjusts the blood to adjust the spleen; The heart main nerve, outside the heart gathers the vessel, resolves, the spleen channels and collaterals to be interlinked at times firmly. Therefore from the heart Tibet alike characteristic is the starting point: Heart for positive dirty (fire dirty), main passes warm, causes the blood to live, to cause the spleen warm, to cause to wind passes, may guarantee gas of the taste, transports the spleen earth healthily, repairs the spleen system's damage, treats spleen defytiency syndrome effectively, therefore heart positive, fire, in the spleen host transports in the process is playing the influential role. Teacher from plans the heart spleen altogether adjusts Fang Yao to treat spleen deficiency syndrome , not only can improve mouse's body weight, the spleen index effectively, the small intestine absorption function, moreover can strengthen the spleen oxidation resistance ability obviously, reduces the lipin peroxidation damage. In the reduced spleen oxidation damage, speeds up spleen weakness repair, the reduction spleen deficiency syndrome treatment course, Therefore, the heart spleen altogether moves in the reduced spleen oxidation damage, speeds up spleen weakness repair, the reduction spleen deficiency syndrome treatment course, enhanced the curative effect, has demonstrated the good application value.