Bufei Jianpi Treatment Of Children With Asthma In Remission Stage Of Clinical Research

Childhood bronchial asthma is the most common chronic non-infectious respiratory disease,its incidence in recent years showed an upward trend in the world,a serious threat to the health of children.Therefore,prevention and treatment of asthma has attracted attention around the world,the World Health Organization have been included in the global prevention and treatment strategies.View of modern medicine to ease the period of the treatment of bronchial asthma should be the core of the treatment。The theme questions Bufeijianpi Decoction who has curing effect and role mechanism in bronchial asthma remission stage.It is directed by chinese and western medical theory and combined clinical work.It is questioned from these two sides.The theoretical part of clinical research through the analysis of ancient literature,combined with modern medical research results,of remission of bronchial asthma pathogenesis,pointed out that the the key of pathogenesis is deficiency of Both Lung and Spleen and retension of phlegm and fluid.It holds that the main treatment of bronchial asthma is invigorating lung and spleen and eliminating wind and phlegm.Clinical studies to Bufei Jianpi with inhaled corticosteroids and inhaled corticosteroid alone treatment contrast observed Jianpi Bufei remission of bronchial asthma treatment efficacy for bronchial asthma in remission stage of the treatment provided an effective method.Method:Clinical study of the selected standards in line with this study of children with asthma in remission stage of 120 cases of patients.120 cases were divided by the random method into the use of the treated group one, the treated group two and the control group,and 40 cases in each group.Treated group one:This group was given glucocorticoid inhalation.A daily dose of mild asthma is 200μg,sub-2 inhalation.A daily dose of mModerate asthma is 300μg,sub-3 second inhalation.A daily dose of s asthma is 450μg,sub-3 second inhalation.This group was given Bufeijianpi Decoction too.The Bufeijianpi Decoction is dissolved in 100-150ml warm water,and taked 2 times a day.Treated group two:This group was given glucocorticoid inhalation.Daily dose is 200/μg,sub-2 inhalation.This group was given Bufeijianpi Decoction too.The Bufeijianpi Decoction is dissolved in 100-150ml warm water,and taked 2 times a day.The control group: glucocorticoid inhalation therapy with the use of the amount of the treated group one.3 groups were observed for 12 weeks.The key indicators:(1)Incidence of the number of times per week 1;(2)Determination of lung function(PEF,FEV₁),recorded before and after medication;(3)Immunoglobulin,peripheral blood eosinophil count,recorded before and after medication.Result:(1)The total effective rate of the 3 groups is 97.55%,95%,92.5%. The difference between the The treatment group and the control group is significantly(P＜0.05).But the difference between the The treatment group one and two is not significantly(P＞0.05).(2)The difference of the incidence number in average monthly between the The treatment group and the control group is significantly(P＜0.05).But the difference between the The treatment group one and two is not significantly(P＞0.05).(3)Three groups can improve the FEV₁,PEF.The difference before and after treatment is significantly(P＜0.05).(4)The eosinophils of the three groups is significantly reduced.The difference before and after treatment is significantly(P＜0.05).But the difference over the same period between the The treatment group one and two is not significantly after treatment(P＞0.05).(5)The IgE of the three groups is decreased after treatment.And IgA,IgG,IgM is increased.Comparison of the treatment group before and after treatment is significantly different(P＜0.05).The control group before and after treatment showed no significant(P＞0.05).Conclusion:In improving the signs and symptoms,improve immune function,the elimination of airway inflammation,to prevent and reduce the number of asthma attacks,the treatment group were better than with the control group.