Huo Gu Pill Avascular Necrosis Of The Experimential Study And Clinical Observation

Objective:Detection of RT-PCR of huo gu pill with liquid nitrogen freezing pill rabbits treated with advanced avascular necrosis of femoral head VEGF and its receptor VEGFR-2 expression to explore the treatment of oral pills INFH living bone disease mechanism and material basis,and in the treatment of this disease the significance of the process.As well as evaluating the huo gu pill on the people avascular necrosis of clinical efficacy.Methods:liquid nitrogen freezing advanced copy rabbits avascular necrosis of femoral head,rabbits were randomly sub-module as follows: Groupâ… :control group,given rabbit bone modulus maru treatment;the second group:the treatment group,rabbits given mode Pills for the Treatment of huo gu pill;Model in the beginning of the third week after delivery,and 1,3,6,9 weeks after administration animals were killed to observe the different stages of femoral head necrosis in VEGF and its receptor VEGFR-2 expression changes.Ficat phases of clinical stageâ…¡avascular necrosis of femoral head for the clinical observation of the object,the application of pure Chinese medicine formulations-huo gu pill,it has Huoxue Huayu Qi,Bushen Zhuanggu Tongluo role.Application of bone health at the same time as the control treatment maru.Experimental observation of treatment by their stageâ…¡treatment of avascular necrosis of the hip before and after the signs and X-ray,CT,MRI changes.Results:The huo gu pill could promote the progress of liquid nitrogen freezing period rabbits ANFH angiogenesis,and with a variety of other ways to promote the treatment of liquid nitrogen freezing avascular necrosis of femoral head in rabbits compared to angiogenesis a longer period of time. Clinical observations show that the improvement of huo gu pill in the hip joint capsules blood,the elimination of hip joint pain,as well as X-line,CT,MRI to show the improvement of femoral head trabecular bone texture or completely normal and cystic areas or new bone formation cystic excellent jian gu sheng pill.Conclusion:The huo gu pill in avascular necrosis of femoral head as early as the mid-term treatment has obvious role.In the treatment of osteonecrosis of the femoral head compared with the control group,the effect is better than jian gu sheng pill,there was a significant difference.