Risk Factor Analysis Of Diabetic Peripheral Neuropathy In Patients With Type 2 Diabetes

Objective: To detect peripheral nerves function by neurometer CPT/C in patients with type 2 diabetes and analyze the relationship with the levels of FPG,HbA1c,lipoidemia,disease duration,BMI,UMA,SCr and ankle-brachial index(ABI).Materials and methods: Patients with type 2 diabetes were detected the peripheral nerves function by neurometer CPT/C from June,2008 to July,2009. Clinical data from 100 positive cases (positive group)which were collected randomly were compared with other 100 negative cases(control group). The duration,BMI,the levels of glycosylated hemoglobin (HbA1c),FPG,total cholesterol(TC),triglyeride( TG ),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol (LDL-C),SCr,UMA and ankle-brachial index(ABI)were analyzed between the two groups. Data were analyzed by SPSS statistic software.Results:Compared to control group,disease duration and BMI increased,the levels of GHbA1c, FPG,SCr,UMA were higher, while ABI were lower in the positive group(P<0.05);the levels of total cholesterol,triglyeride and low density lipoprotein-cholesterol were higher, the levels of high density lipoprotein- cholesterol were lower in positive group,but the differences were not statistical significant.Conclusion:Peripheral nerves dysfunction of patients with type 2 diabetes were related to BMI,disease duration,the levels of blood glucose ,SCr,UMA and ABI. Multi-influencing factors contribute to the diabetic peripheral neuropathy,and it is advantageous to prevent the development of diabetic microangiopathy especially diabetic peripheral neuropathy by good blood glucose management.