| Insomnia, a disease that can not get normal sleep usually, influence people's normal work,life,learning and health. The incidence of insomnia is high in contemporary society. Western medicine often uses benzodiazepine drugs for insomnia patients at present, not only it produces a lot of side effects if this kind of drug was used by a long time, but also would create dependence. TCM therapy has an obvious curative effect for insomnia, less side effects, but not yet completes TCM syndrome differentiation, so it is worth to study further to relieve the physical and psychological suffering of patients with insomnia.Objective:At present, we have not pay enough attention or take a deep investigation to insomnia of kidney-Yang deficiency in clinic, therefore this study attempt to expatiate the disease cause and pathogenesis of insomnia for kidney-Yang deficiency, observe the curative effect and safety of warm the kidney,calm and suppress the sthenic yang for insomnia which is kidney-Yang deficiency syndrome. Showing that insomnia for kidney-Yang deficiency exists objectively, on the other hand, to perfect the TCM therapy on insomnia.Methods:Utilizing the method of random,control,and forward-looking of clinical research. According to random number by the software SPSS 17.0, we divided the patients who conform to the standards randomly into the treatment group and the control group,30 cases each observation treatment. The treatment group was given Wen Shen Zhen Qian Ru Mian Tang and the control group was given ESTAZOLAM tablets, After 30 days treatment ends, we observed the symptoms and signs of the patients before and after treatment, the safety and adverse reaction of the drugs. The SPSS statistical software 17.0 was used to analyze the data.Results:The research including 60 patients with insomnia that was kidney-Yang deficiency syndrome, the two groups in treatment were equilibrium by age,gender,patient's condition,Pittsburgh sleep quality index (PSQI) score and TCM symptoms integral, there was no significant differences between the two groups (p>0.05), it was comparable in them. The clinical observations showed that the total effective rate of the treatment group was 90%, while the control one 86.7%, the difference of the total effective between both two groups was not significant (p>0.05), it suggested that the two groups have the same curative effect; The PSQI scores of the two groups were significant difference before and after treatment (p<0.05), showed that the two drugs on patients with insomnia were effective, the treatment group compared with the control group after treatment, there was no significant difference (p>0.05), the result suggested that the two drugs have the same curative effect. While for the total integral of TCM, there was significant difference before and after treatment (p<0.05), showed that the treatment group and the control group were both effective in improving the total integral of TCM, the treatment group compared with the control group after treatment, there was significant difference (p<0.05), the treatment group decreased more points, showed the treatment group was better than the control one; and the treatment group could relieve the pain of extreme chilliness,body tired and laziness,the weakness of waist and knees obviously, it was superior to the control group(p<0.05). In the clinical course of treatment, 18 patients in the control group was discomfort about dizziness, lightheadedness caused by medications, but we had not found drug adverse reaction during the patients took Wen Shen Zhen Qian Ru Mian Tang, it was safety.Conclusion:TCM therapy has its unique advantages for insomnia. It is effective to use the therapy of warm the kidney,calm and suppress the sthenic yang for insomnia which is kidney-Yang deficiency syndrome, extends sleep time and improves the clinical symptoms. Drug adverse reaction has not been found in the treatment process, so it is valuable for further research and spread.
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