The Clinical Value Of Cine MR Imaging In Ventricular Function Assessment And MRCA

Objective:To study the clinical value of cine MR imaging in ventricular function assessment and MRCA.Methods:36 healthy volunteers and 14 patients with cardiac disease were examed with breath-hold true FISP cine MR imaging sequence and amended localize methods. Healthy volunteers also accepted Echocardiography as left ventricular function contract. Left and right ventricular function and myocardial thickness were analyzed and assessed with the Argus software of cardiac evaluation.21 healthy volunteers were underwent navigator-echo 3D MR coronary angiography by breath-hold and free-breathing techniques. The percentages of visualization of coronary artery segments with two techniques were evaluated.Results:1. MR measured left ventricular global function of normal group:EDV 101.25±19.22ml, ESV 42.08±13.26ml, SV 69.17±9.78ml, EF 59.09±7.16%; Right ventricular global function:EDV 118.87±27.12ml, ESV 57.64±16.09ml, SV 61.23±12.70ml, EF 51.85±4.47%.2. There was no statistical significant difference in EDV between MRI and Echocardiography. But ESV measured by MR was higher than Echocardiography. Other parameters were lower than Echocardiography. The r value of two methods changed from 0.62 to 0.80(p<0.05) and had good relationship.3. In the middle slice of interventricular septum, the anterior wall of the LV was the thinnest and the posterior LV wall was the thickest. There was statistical significant difference between segments around circumference in end-diastole, but there was no difference in end-systole.4.The LV diastolic function was analyzed in the short-axis of middle slice of interventricular septum:PER 3.71±0.95 EDV/sec,PFR 3.50±0.74 EDV/sec,TPER 107.74±51.96 msec,TPFR 143.87±34.05 msec.5. The change of morphology and ventricular function in vary cardiac diseases were also depicted and assessed.6.52% of each coronary arterial segments were shown by breath-hold and free-breathing techniques in MRCA. The percentages of visualization in other segments of coronary artery were following:RCA proximal and LM 100%; RCA middle, LAD proximal and LCX proximal more than 65%. LCX distal zero.Conclusion:1.MRI could exam cardiac diseases noinvasively and accurately included morphology and ventricular function.2. Cine MR imaging combined with amended localizer might accurately evaluate left and right ventricular function with high reproducibility. It is of great value in clinical application such as diagnosis and following detection.3. Proximal and middle portions of the major coronary arterial branches can be visualized with navigator-echo 3D MR coronary angiography. Its imaging is easily influenced by many factors. With its techniques and sequences development and innovation, MRCA could more exactly detect coronary artery and stenosis for satisfying clinical needs and become an important noinvasive exam method.