Correlation Analysis Between Ankle-Brachial Index And Hypertension In Patients With Lowerd Extremity Arteriosclerosis Occlusive Disease

Objective:By investigating the association between ankle-brachial index(ABI) and hypertension in hospitalized Patients with lower extremity arteriosclerosis occlusive disease(LEASOD) to Provide a certain basis for the research of the cause of LEASOD, and its Prevention, as well as the clinically target-oriented treatment.Methods:The objects of present study were selected from Patients with LEASOD, who were consecutively admitted to the division of general surgery in first affiliated hospital Shan Xi Medical university from January 2005 to June 2010. After collecting their clinical information such as the highest DBP, the highest SBP, the average DBP,the average SBP,PP, the history of hypertension, diabetes mellitus (DM), ABI value, gender, age, height, weight, Coronary heart disease, stroke and smoking, blood lipid Profile, fibrinogen(FIB) and so on, we chose 92 Patients whose data was complete. All subjects were divided into three groups based on ABI values,0.7≤ABI≤0.9 for mild LEASOD group,0.4≤ABI<0.7 as moderate, ABI<0.4 for severe. X2 Test or One-Way ANOVA were used to compare among the three hypertension groups the prevalence rate of hypertension PP,the highest DBP, the highest SBP, the average DBP,the average SBP, the duration of hypertension.Multiple linear regression analysis was Performed to Evaluate the correlation between ABI and each of the above-mentioned risk factors, and analyse the reasons.Results:1.There were no significant differences in average systolic blood Pressure(SBP),average diastolic blood Pressure(DBP),the highest SBP,the highest DBP,the prevalence rate of hypertension PP,Among the three groups.2.The differences of ABI value, duration of hypertension were statistically significant Among the three groups, these variables were given P values of<0.001,0.009, respectively. But, only the multiple comparisons of ABI value among the three groups showed the differences of them were statistically significant (P<0.001).3.Multiple linear regression results indicated that ABI correlated significantly with gender, age, hypertension, DM, HDL-C and the duration of smoking.Conclusion:1.The patients with lower ABI value(namely, the more serious condition), were often a longer history of hypertension.2.Decrease of the concentration of HDL-C,hypertension,DM,long-term smoking, gender and increase of the age were the major factors aggravating LEASOD.HDL-C has a Protective effect on LEASOD.