Corelation Analysis Between Ankle-Brachinal Index Andd Smoking Index In Patients With Lower Extremity Arteriosclerosis Occlusive Disease

Objective:By investigation the association between ankle-brachial index (ABI) and smoking in hospitalized patients with lower extremity arteriosclerosis occlusive disease of the disease.To provide a certain basis for the research of the LEASOD, and its primary,secondary prevention, as well as the clinically target-oriented treatment.Methods:The objects of present study were selected from patients with LEASOD, who were consecutively admitted to the division of general surgery in first affiliated hospital Shan Xi medical university from January of 2005 to October of 2010. After collecting their clinical information such as gender, age, height, weight, blood pressure, ABI value, blood lipid profile, fibrinogen (FBI), the history of hypertension, diabetes mellitus (DM), dyslipidemia, coronary heart disease, smoking and so on, we chose 86 patients whose data was complete. All subjects were divided into three groups based on CI values, CI<200 for mild smoking group,200400 for severe(The WHO in 1984 about smoking survey methods standards). Single factor analysis of variance was used to compare ABI values among the three groups, and spearman rank correlation analysis was used to evaluate the correlation between CI and ABI. All subjects were divided into three groups based on ABI values,0.7 0.05. The differences of age, duration of hypertension, DM duration, TC, HDL—C, FIB, the prevalence of DM and hypertension were statistically significant among the three groups of ABI, these variables were given P values of.<0.05.2.Multiple linear regression results indicated that ABI correlated significantly with gender, age, hypertension, DM, TC, HDL—C,FIB and the grades of smoking index.3. Spearman rank correlation analysis results indicated that CI grades correlated significantly with hypertension, DM, TC and HDL—C.4. The difference of ABI was statistically significant among the three groups of CI, and CI grades correlated significantly with ABI.Conclusion:When the smoking index was high, the LEASOD patient's ABI and HDL—C value would be low, their merger rate of hypertension and DM as TC value would be high. The factors of the above would aggravate patient's conditions. Smoking was not only the independent risk factors and the influence of above factors would worsen the symptoms in patients of LEASOD.