| Heshouwu comes from the plant Rhizome of Polygonum multiflorum Thunb, which is a special medicine of Si chuan.2010 edition of "Chinese Pharmacopoeia" in the processed products included only Radix P. multiflori Preparata (steamed/ processed by the milk of Sojae senmen nigrum), along with the development of modern processing technology, Radix Polygoni multiflori of fermentation as a new type of fermentation product are widely used in medicine and has begun to health care productsand so on. In view of the use of Radix Polygoni multiflori of fermentation growing year by year, the current study its chemical composition is not systematic, not yet developed a set of perfect quality standards. This study received Radix Polygoni multiflori of fermentation and pharmacopoeia contained Tuber species and processing ground and underground parts of the system, main contents and results are as follows:In physical and chemical identification, we identificated the Radix P. multiflori processed product powder by microscope, that can be directly observed by the processing, some change in microstructure, such as clusters of calcium oxalate and starch grains decreased or disappeared, to promote the material basis for In-depth study. Research on TLC, we do check on the 2,3,5,4'—tetrahydroxy—stibene—2—O—β—D—glucosid, amino acids and anthraquinones, separation is good. In the choice of color reagent and expand agents has been expanded, and all are one-time, compared with the method on pharmacopoeia is simple quadratic expansion.In terms of Content determination, we resarch systematically in the chemical composition for the Polygonum in different medicinal parts and different processed products. In addition to determine the content of 2,3,5,4'—etrahydroxy—stibene—2—O—β—D—glucosid and bound anthraquinones by the methods according to Pharmacopoeia, but also are the types of its component phospholipids (phosphatidylinositol, PI) and the content of the type of tanning Constituents (gallic acid, catechin), and content, the type of amino acid composition and content, as well as reducing sugar and polysaccharide content were determined. The results showed that the chemical composition were significantly different in different medicinal parts of Polygonum, after processing by different methods also show the chemical composition changes in different proportion.This study is not solely of a blind study medicine, but rather as the center of Polygonum multiflorum, with their different medicinal parts (Rattan of Polygonum multiflorum), traditional processed products (steamed/processed by the juice of Sojae senmen nigrum), the modern processed products (Radix Polygoni multiflori of fermentation multiflorum), even in the HPLC fingerprint rearch it was also introduced the same family but different species piant (Polygonum, Rhubarb), for the material basis for the comparative study. Covering a wide range of each other closely, as a ring its interlocking system to study. In addition, Introduced the concept of "processing materials affects the material basis of the Processed Product" point of view fistly, in the processing accessories (black soybean milk, yellow soybean milk) Comparative study further revealed the role and mechanism of processing.In this paper, Studied on the characters of the total extracts of quality control, including identification, inspection, determination. Establish a TLC identification method; moisture, ash, total tannins were examined; established 2,3,5,4' Ttetrahydroxy—stibene—2—O—β—D—glucosid, anthraquinones of HPLC determination method; developed quality standards for Radix Polygoni multiflori of fermentation draft. So the standard of 2,3,5,4'—tetrahydroxy—stibene—2—O—β—D—glucosid content is not less than the provisional 1.0%, free of anthraquinone is not less than 0.05% of total anthraquinone. We made a draft about quality standards for total extracts of Radix Polygoni multiflori of fermentation.Innovation:1. For the first time, we identificated the Radix P. multiflori processed product powder by microscope, that can be directly observed by the processing, some change in microstructure, such as clusters of calcium oxalate and starch grains decreased or disappeared.2. Research on TLC, we do check on the 2,3,5,4'—tetrahydroxy—stibene—2—O—β—D—glucosid, amino acids and anthraquinones,in the choice of color reagent and expand agents has been expanded, and all are one-time, compared with the method on pharmacopoeia is simple quadratic expansion.3. For the first time established a PI content determined by TLC-scanning method, the method is simple, fast, reproducible, accurate and reliable.4. For the first time, Radix Polygoni multiflori of fermentation, Radix P. multiflori Preparata, Rattan of Polygonum multiflorum and amino acid content in a comparative study.5. For the first time comparative study on the phospholipid in processing accessories (black soybean milk, yellow soybean milk), to provide the basis for the screening of materials.6. Established a quality standard of Radix Polygoni multiflori of fermentation fistly...
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