Different TCM Syndrome Type Patients With Ulcerative Colitis Appear IL-6,IL-8 Level Of Research

Objective:different syndromes in patients with ulcerative colitis cytokines IL-6, IL-8 levels of study during which the internal law, to regulate traditional Chinese medicine clinical diagnosis and treatment of patients with ulcerative colitis, immune disorders, alleviate the pathology of autoimmune status to provide theoretical foundation and objective indicators. Methods:Western diagnostic standards, the collection cases of ulcerative colitis, clinical investigation, completed questionnaires and TCM colonoscopy performance of the original registration form, is divided into six syndromes:damp card, qi stagnation card, spleen and stomach card, spleen deficiency syndrome, Yin and Blood deficiency syndrome, the liver spleen deficiency, which permits damp, qi stagnation true card card card weak stomach, spleen deficiency syndrome, deficiency syndrome is Yinxue deficiency, the liver mixed with spleen deficiency is the actual situation permits. Detected by radioimmunoassay in patients with ulcerative colitis and normal controls cytokine IL-6, IL-8 values. With the appropriate statistical methods, for statistical analysis. Results: 1.180 cases of UC patients the distribution of TCM were:damp card> weak stomach card> Liver Spleen deficiency> qi stagnation card> spleen deficiency syndrome> Yin and Blood deficiency syndrome, which damp cards, accounting for 28% of all patients.2. Ulcerative colitis patients in the TCM-based IL-6, IL-8 levels higher than normal (P <0.001).3. Qi stagnation damp cards and certificates IL-6, IL-8 levels than the spleen and stomach card, spleen deficiency syndrome, Yin and Blood deficiency syndrome, the liver spleen deficiency is high, the difference was statistically significant (P<0.05); card damp Qi stagnation between the card and IL-6, IL-8 levels were no significant differences (P> 0.05), spleen and stomach card, spleen deficiency syndrome, Yin and Blood deficiency syndrome, the liver between spleen deficiency, that deficiency with the actual situation permits inclusion of the syndrome between IL-6, IL-8 was no significant difference (P> 0.05).4. In active ulcerative colitis, positive dominant, in remission, deficiency, actual situation permits inclusion dominant activity of IL-6, IL-8 levels higher than remission, the difference was statistically significance (P<0.05); activity and remission of IL-6, IL-8 levels higher than the normal control group, the difference was statistically significant (P 0.001). Conclusion:1. Ulcerative colitis distribution of the different syndromes, which permits up to damp, at least Yinxue deficiency syndrome.2.UC the entire course of the disease exist in patients with immune disorders, pro-inflammatory cytokines IL-6, IL-8 levels higher than normal.3.UC patients with positive IL-6, IL-8 levels than the deficiency, the actual situation permits inclusion, hence the IL-6, IL-8 for TCM syndrome, especially in the actual situation to provide some reference syndrome.4. UC patients with activities of IL-6, IL-8 levels higher than in remission, so the IL-6, IL-8 in UC staging also has certain reference value.