| Objective: To study the therapeutical effect of the decoction of Bu-Shen-An-Geng on peripheral menopause syndrome(PMS), and explore its action mechanism. Methods: We selected 60 patients with PMS, observe the clinical symptoms' improvement after treatment and detect the concentrition of E2,FSH,LH,β-EP,IL-2,PTH,CT in the blood. Conclusions: The clinical symptoms are significantly improved and the clinical total efficiency is 96.7%. The improvement of Kupperman scores is very significant (P<0.01). After treatment, the concentrition of FSH, LH in the blood is significantly lowered, while the concentrition of E2 in the blood is significantly raised (P<0.05). The concentrition ofβ-EP,IL-2 is significantly evaluated after treatment (P<0.05). The PTH is remarkblely reduced, and CT is raised (P<0.05). Conclusions: The decoction of Bu-Shen-An-Geng has extremely precisely therapeutical effect on PMS. And the mechanism might be related to regulating theneuroendocrine-immune Network as a whole. The study achievements provide new thoughtways and methods. |
