Technological Innovation Of Jin Gang Teng Capsules And Pharmaceutical Research

Smilax china L. popularly known in China as "Jin Gang Teng".It is commonly used Chinese medicine, which was collected in the "the Chinese pharmacopoeia"in 2005 version,It has various pharmacological effects including Xiaozhongzhitong and Huoxuehuayu and so on. On clinic, it commonly used to in the treatment of the various gynecological inflammatory diseases, efficacy significantly. The current clinical use of inflammatory diseases, efficacy significantly. The current clinical use of Pharmaceutical Company by the traditional production technology. To improve its content, macroreticular resin purification technology was applied for isolating and Purifying an effective part group of Jin Gang Teng. The molding process, quality standards and preliminary stability of Jin Gang Teng capsules were researched in the article. It laid the foundation for redevelopment of Jin Gang Teng Capsules.The molding process of Jin Gang Teng capsules were studied by single factors; examining the types, amount of accessories and the relative humidity of particle which provide a theoretical basis for an industry to controll workshop production conditions. With Quercetin, diosgenin as reference substance, using TLC method to identify the ethanol extract of Jin Gang Teng capsules. With rutin, diosgenin as reference substance, UV-VIS spectrophotometry was used to detect total flavonoids, total saponins of Jin Gang Teng capsules; using HPLC method to analysis quercetin and diosgenin content. The quality standard were improved which can provide a basis for quality control.Preliminary stability of Jin Gang Teng capsules were researched,which show that Jin Gang Teng capsules stability in 6 months. It provide reference for the redevelopment of Jin Gang Teng capsules.