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Influenza A H1N1 Influenza Dialectical Mode Of Staging Studies, The Clinical Features And Efficacy Of Combination Of Chinese And Western Medicine

Posted on:2011-10-24Degree:MasterType:Thesis
Country:ChinaCandidate:Z XiaFull Text:PDF
GTID:2154360308477041Subject:Traditional Chinese Medicine
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ObjectiveInfluenza A H1N1 influenza is an acute and infective respiratory disease, the pathogen is a new type of influenza A H1N1 influenza virus,which is easy to spread among people. In order to clearly understand the characteristics of influenza A H1N1 influenza and take better control measures; we observed the new Influenza H1N1 influenza syndrome in patients with features, described the pathogenesis and the mode of differentiation stages,and therapic efficacy of Integrated Chinese and Westen Medicine.MethodAccording to the Ministry of Health Influenza HINI influenza diagnostic criteria, we selected 308 patients diagnosed with H1N1 influenza in the three hospitals from March 2009 to January2010, which are Shenzhen Third People's Hospital, Guangzhou 8th People's Hospital, Beijing You'an Hospital. Retrospective analysis of 308 cases summarized 17 cases of critically ill patients with mild as well as their respective epidemiology, from the country, age, weight, length of hospital stay, fever (including the highest incidence of body temperature, fever duration, and treatment-the normal body temperature time), virus detection (including viruses duration of treatment-the virus clearance time), admission blood before and after the change, and patients with severe complications, the treatment situation and prognosis; Cross-sectional retrospective survey methods used were in accordance with the table Securities, Securities and recovery in three stages, the respective statistics were 308 cases of clinical symptoms and signs, as well as evidence of the relevant factors analysis; Finally,172 patients with complete data were given medicine Tamiflu, and the Chinese Jia Dafei treatment, record their own heat (including the highest incidence of body temperature, fever duration,and treatment-body temperature normal time), virus (including virus, the duration of treatment-HIV negative time), and admission blood before and after the change in control of the observations.Results(1) 308 cases with mild influenza A H1N1 influenza patients possessed the history of exposure to H1N1; who mostly occurred in 16-30 year-old; fever is the main clinical manifestations, and most of moderate fever, duration of fever is about 21-80 hours; For the duration from onset of symptoms to the virus detected negative, the average was 5.71±1.89 days; For the duration from treatment to virus detected negative, the average was 4.25±1.78 days; For the peripheral white blood cell counts, there was no statistical difference between pre-treatment and treatment (P>0.05). More than 17 cases of severe disease occurred in children 2-12 years of age. There are 10 cases with temperature above 39℃. The main complication was pneumonia, which was 15 cases,4 cases occured multiple organ dysfunction,4 cases had basis of disease. 9 cases had abnormal liver function, myocardial enzyme abnormalities occurred in 7 cases,9 cases with abnormal electrocardiogram. Duration of virus from the onset of symptoms was mostly for 2-7 days; For the duration from treatment to H1N1 virus detected negative was mostly for 1-4 days.7 cases received combination of oseltamivirir and TCM drugs treatment,5 cases only received TCM herbs,2 patients only received oseltamivir treatment. There were 3 cases who did not receive oseltamivie or TCM hers.16 cases recovered and 1 patient died.(2) 308 cases of patients with evidence of the relative frequency table signs, symptoms include: fever, fatigue, cough, aversion to cold, pharyngeal congestion, swollen tonsils, etc.; in Securities are: fever, cough, yellow urine, thirst, upset, sore throat, etc.; recovery are:fatigue, poor appetite, abdominal swelling of the liver, yellow urine, cough. Prime Securities card table in order to wind-heat, deficiency of qi and phlegm-based, where evidence of fire by Yu, Qi and phlegm main damage recovery to restore justice (qi, yin, yang), I is not evil characteristics of the net for the pathogenesis.(3) 172 patients were given treatment in the virus clearance time, the Tamiflu group and traditional Chinese medicine+Duffy was no significant difference (P>0.05), from the drugs-the virus clearance time, the Chinese+Duffy Group Tamiflu is also compared groups was not significant (P>0.05). The two groups in the pathogenesis of the highest temperature, but without statistical significance (P>0.05),while in the drug-the temperature drops, the Chinese+Tamiflu Tamiflu group compared with the normal time set temperature faster, more statistically significant (P<0.05). Blood leukocytes, the Tamiflu treatment group was statistically significant before and after (P<0.05); the Chinese+Duffy groups was not significant before and after (P>0.05).Conclusions(1) Influenza H1N1 influenza were mostly self-limited disease, most patients can be diagnosed, even if timely treatment of critically ill patients, most can be cured, prognosis is good.(2) in patients with influenza A H1N1 influenza facie evidence of the passage of heat to the wind table, healthy atmosphere characterized by impaired, where evidence of similar to the "air temperature" disease "hot Yu mediastinoscopy permits" and "Evil Heat Obstructing Lungs" of the combination of damage recovery to restore justice (qi, yin, yang), I is not evil characteristics of the net for the sick machine.(3) Influenza H1N1 influenza morbidity in patients with the highest temperature, the virus clearance time on whether the Chinese intervention, comparison, no significant difference. In the treatment-the normal temperature time, the improvement of symptoms, reduce complications and so on, better than Western medicine+Tamiflu treatment.
Keywords/Search Tags:A flow, H1N1, stages dialectical mode, Combining Chinese and Western medicine
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