Application Of SPECT For Lying To A State Of Functional Areas Of The Brain-Auditory Stimulation Of The Brain Changes In Functional Areas

IntroductionIn judicial practice, the suspect (accused) of the statement, the party's statements and testimony of witnesses and other evidence of subjective evidence of the lack of corresponding chain that, through the polygraph test to prove whether the evidence that these subjective authentic is critical. However, the current polygraph techniques rely mainly on multi-channel polygraph, according to ECG, blood pressure, respiration, skin resistance and other physiological indicators of autonomic responses were seized indirectly determine whether the lie, there is a false positive or false negative results, the test results in judicial proceedings can not be directly used as conclusions. Therefore, to determine brain function in the area lying under the change in the future play an important role to solve the problem lie detector test.SPECT is a special probe of its nuclear-ray probe, in vivo detection of radioactive substances (drugs radionuclide 99mTc) to examine the distribution, you can observe the brain activity of the functional areas of thinking changes in status.This study was conducted on 15 subjects SPECT brain scan, and then of lying and telling the truth in a state of different brain areas to change to lying state of the neural network.Test Object and MethodTest subjects15 healthy volunteers were right handed, male, aged 23 to 28 years old. There was no spirit in all subjects with a history of nervous system diseases and related. Volunteers are the details about the purpose of this study, contents and steps voluntarily to the examination.Test MethodA total of 15 subjects were measured three times each (ie. resting scan. telling the truth and lying under scan mode scan), points 3 days. Each time after injection ECT scan, while asking a question. Question:Your mother's family name? Answer:If surname "Lee" (speak the truth) or the surname "Chang" (telling lies). After completion of test to confirm. Concrete steps are as follows.1.the first day (resting scan)Subjects were the establishment of intravenous access, relax the body sit in the scanning bed. Subjects could turn a blind eye to rest, remove miscellaneous considerations.5 minutes start resting injection, and for ECT scan.2.the next day (to tell the truth mode scanning)Subjects were the establishment of intravenous access, relax the body sit in the scanning bed. Subjects could turn a blind eye to rest, remove miscellaneous considerations. Resting injection started 5 minutes. and scanned for ECT, while asking a question. Subjects were immediately answered (to tell the truth) problems.3. the third day (lying under scan)Subjects were the establishment of intravenous access, relax the body sit in the scanning bed. Subjects could turn a blind eye to rest, remove miscellaneous considerations. Resting injection started 5 minutes, and scanned for ECT, while asking a question. Subjects were immediately answered (that lies) issues.Parameter DesignAcquisition matrix:128 x 128, to peak:140keV. window width:±20%. Acquisition mode:ZOOM:1.45. probe the rotation 1800,5.6/frame, each frame acquisition 25s, were collected from 64 images, acquisition time of about 30min. Statistical analysis-SPM analysis:In this study, SPM2 (SPM2, Wollcome Department of Cognitive Neurology, London, UK) analysis of changes in brain function area. Analysis process, including image conversion, image standardization, statistical analysis and significant assessment 4 main steps. SPM2 software by cross-section of all SPECT images into analysis7 formats. in MATLAB6.1 platform, application SPM2 the image processing and data analysis. First of all, according to procedures within the SPM SPECT template that comes with the image normalized to the average level of regional cerebral blood flow 55ml/100ml/min normalization, be adjusted in the brain areas activated image, so that with the Talairach's corresponding space coordinates. We will compare the adjusted data can be obtained by the numerical composition of a series of t statistical parametric map SPM (t), (voxel threshold difference is set to 10), then SPM (t) maps were converted into the standard is state distribution of the Z parameter map SPM (Z), SPM (Z) on each of the differences were significant by t test on the data (p= 0.05) to evaluate [1]. Then according to Talairach map projected onto the corresponding brain regions that are lying areas when the brain activation.ResultsTell the truth and lying state than lying back under pillow, insula, medial temporal lobe, frontal gyrus, anterior cingulate cortex, hippocampus and cerebellum significantly increased the radioactive distribution.ConclusionLying brain areas identified for the pillow back, insular, in the temporal lobe, frontal gyrus, anterior cingulate cortex, hippocampus and cerebellum.