| ObjectiveBy collecting the epidemic information and information collected by Traditional Chinese Medicine (TCM) four diagnosis methods, advanced diagnostic tools and statistical methods, conclude the factors related to onset of Reflux Esophagitis (RE), analyze the nature of disease, disease location and other syndrome elements, thereby discuss the pathomechanism of RE in order to provide a basis for clinical diagnosis, treatment and study of this disease.MethodsFormulate a RE epidemiology and TCM four diagnosis questionnaire on the basis of literature study. Collect the general information and four diagnosis information of RE patients. Use Microsoft Excel to create a data base, and by using descriptive statistical analysis and variance analysis to analyze the relationship between RE and factors affecting it. By using factor analysis method to explore the disease nature, disease location and other syndrome elements of RE in TCM perspective.ResultsA total of 275 cases were collected, with 152 (55.3%) males and 123 (44.7%) females, with a ratio of 1.26:1. The youngest aged 19 to 74, with an average age of 51.31±12.095, the occurrence is highest in middle age group (44%), followed by elderly group (29.82%) and youth group (26.18%). The occurrence is significant higher in males than female in the youth group. RE is highest in patients with normal weight range (41.8%), followed by overweight (38.5%), obese (17.10%), and underweight (2.55%). We found that occurrence of RE is highest in retirees and unemployed (52.32%), followed by administrators (11.644%), finance and service line employees (10.55%), self-employed (10.18%), technicians (8%), others (4.37%). More than 90% of RE patients have secondary education and above. Diet and lifestyle:Ingestion of fatty and oily food (46.91%)>ingestion hot food(31.27%)>strong tea (30.55%)>food high in salt content (29.45%)>spicy food (28.365%)>sweet food (22.18%)>preserved food (20%)>fried food (17.45%)>coffee or chocoloate (16.73%)>sour food (13.82%)>ingestion of cold food (6.18%)>carbonated drinks (4.36%).89 cases(32.36%)had alcohol history,77 cases(28%)had smoking history, irregular meals (30.18%), overeating (37.09%), ingestion 2hrs before bed (13.09%). Factors inducing onset of RE:diet (42.19%), climate (16.16%), emotions (14.25%), exhaustion (6.31%), drug related (1.64%). Emotionally, irritability is the most common abnormal state seen (58.18%), followed by anxiety (19.27%), nervousness (14.18%), depression (5.82%). Occurrence of RE is related to Hp infection. Occurrence of Hp infection is higher in RE patients as compared to non infected patients.The results from questionnaire found that reflux (71.6%) and heartburn (70.9%) are the main symptoms, bloating, belching, throat discomfort. Statistical results found that the main disease location is at liver, stomach, spleen. The disease nature is mostly excess syndrome, presented as heat, qi stagnation, and phlegm. The deficiency syndrome mostly present as qi deficiency and yang deficiency.ConclusionThe occurrence of RE is highest in middle age group, and is significantly higher in male than female in youth group. The occurrence of RE is related to weight, diet, season, emotion and Hp infection. The disease location of RE is in liver, stomach, and spleen. The disease nature is mostly excess syndrome, presenting as heat, qi stagnation, phlegm, deficiency syndrome is mostly qi deficiency and yang deficiency. |
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