Study On The Correlation Between TCM Syndromes And Clinical Factors In 55 Cases Of Chronic Uric Acid Nephropathy

Objective:This study research Syndrome Distribution of chronic uric acid nephropathy and correlation with clinical factors, based on the basic data, clinical symptoms and laboratory tests, for reference TCM disease differentiation-Differential Treatment of chronic uric acid nephropathy.Methods:Using clinical retrospective study,we collected the clinical data of 55 patients with chronic uric acid nephropathy. This study collectes patient’s sex, age, weight, renal function, blood lipids, blood coagulation, routine blood, routine urine and kidney ultrasound and TCM information, including the main clinical symptoms and tongue mai.55 patients with chronic uric acid kidney disease aredivided into 4 types of empirical syndorome and 5 types of deficiency.SPSS20.0 statistical software is used for data analysis.The distribution of TCM syndromes as well as each syndrome in clinical experimental index differences and relevance.Result:This study were observed 55 patients,including 45 males and 10 females, male to female ratio is 4.5:1,and male higher than female. The youngest patient was 25 years old, the oldest is 87 years old. The difference in age distribution is statistically significant,50-59 years is most, accounting for 23.6%, followed by 60-69 years old accounted for 21.8%. Overweight and obese patients accounted for 80%, normal body mass index were only 20%, the difference is statistically significant.55 patients include 4 pure empirical cases which are inner-accumulation of damp-heat syndrome, and the remaining 51 patients belong to deficiency combined with empirical syndrome. The number of each syndrome in 51 deficiency cases from high to low is spleen and kidney qi deficiency, liver and kidney yin deficiency, deficiency of both qi and yin, spleen and kidney yang deficiency, deficiency of both yin and yang, the distribution of the difference was statistically significant. The number of each syndrome in 55 empirical from high to low is inner-accumulation of damp-heat syndrome, static blood obstructina collaterals syndrome, phlegm internal blockage syndrome, cold-dampness arthralgia spasm syndrome,distribution difference was statistically significant. Differences between in deficiency and empirical of 51 deficiency combined with syndrome cases is statistically significant, of which the more significant is that spleen and kindey qi deficiency syndrome is multiple associated with inner-accumulation of damp-heat syndrome,as well as liver and kidney yin deficiency syndrome is multiple associated with static blood obstructina collaterals syndrome.The difference of each syndrome in BMI、TC、TG、HDL-C、LDL-C、BUN、UA、SCr、 PT、APTT、TT、FIB、WBC、RBC、HCT、PLT、Kidney stones、urine protein、urine pH was not statistically significant. Empirical Comparison of the syndrome marked on platelet count in the overall difference was statistically significant, multiple comparisons show damp syndrome platelet count was significantly higher than blood stasis syndrome, cold Blockage card. The empirical standard into damp syndrome and non-damp syndrome, platelet count Logistic regression analysis showed that damp syndrome associated with platelet count, platelet count and the higher the greater the likelihood of damp Syndrome. Blood uric acid and cholesterol, body mass index correlation studies suggest no significant difference.Analysis conclusion:There are more men than women who have chronic uric acid nephropathy, mostly in 50-59 years old, followed by 60-69 years old. The pathogenesis of this disease is the deficiency combined with syndrome,. Spleen and kidney qi deficiency are more accompanied by inner-accumulation of damp-heat syndrome, and liver and kidney yin deficiency are often followed by static blood obstructina collaterals syndrome. The platelet counts of patients who are inner-accumulation of damp-heat syndrome are significantly higher than patients who are static blood obstructina collaterals syndrome and cold-dampness arthralgia spasm syndrome. Furthermore, the platelet counts are associated with inner-accumulation of damp-heat syndrome in some extent.