A Survey Of Traditional Chinese Medicine For Treating Primary Dysmenorrhea

Objective:To provide some proposal for TCM treating primary dysmenorrhea by summarizing the TCM syndrome differentiation, therapeutic methods and principle of using medication from literatures of tradition Chinese medicine treating primary dysmenorrhea for the past 10 years.Method:Trials were identified from Chinese National Knowledge Infrastructure Database (CNKI) from January,1 2006 to December,31 2015. Search terms were "traditional Chinese medicine treat primary dysmenorrhea." The database is built by EXCEL software based on the qualified literatures and divided into syndrome type, treatment and medication.Data and Methods:(1) Extracting the number of cases, TCM syndrome types, treatment, medication form qualified literatures. (2) Calculating the total number of cases, the ratio of each type of syndrome and treatment and drawing diagrams. (3)Calculating the ratio of each Chinese medicine in every TCM syndrome types and treatment, sorting from top to bottom, creating a form of first 12th important channel tropism, properties and flavors. Analyzing and summarizing the frequently medication in the modern pharmacological aspects to summarize the common TCM syndrome differentiation, therapeutic methods and principle of using medicationResult:1 The common TCM syndrome differentiation and therapeutic methods: ①the ratio of cold congealing and blood stasis/total is 42.18%, the therapeutic principle is to warm the channels and dissipate cold, dissolve stasis and relieve pain; ②the ratio of qi stagnation and blood stasis/total is 37.15%, the therapeutic principle is to rectify qi and move stagnation, dissolve stasis and relieve pain; ③ the ratio of kidney-deficiency and blood stasis/total is 9.33%, the therapeutic principle is to invigorate blood and supplement kidney, dissolve stasis and relieve pain;④the ratio of qi deficiency and blood stasis/total is 3.63%, the therapeutic principle is to supplement qi and nourish the blood, dissolve stasis and relieve pain; ⑤the ratio of qi and blood deficiency/total is 3.05%, the therapeutic principle is to boost qi and nourish the blood, rectify menstruation and relieve pain. Cold congealing and blood stasis, qi stagnation and blood stasis comprise about 79.33% of the total.2 Commonly used Chinese medicine for syndrome types of primary dysmenorrhea:Cold congealing and blood stasis: Chinese angelica、 Sichuan lovage root、 corydalis rhizome; yanhusuo、 nutgrass galingale rhizome、 fennel、 red peony root、 white peony root、 cassia bark、 flying squirrel faeces、 combined spicebush root、 medicinal evodia fruit、 tree peony bark; Qi stagnation and blood stasis:corydalis rhizome、 Chinese angelica、 red peony root、 peach seed、 prepared liquorice root、 Sichuan lovage root、 bupleurum、 Safflower、 orange fruit、 nutgrass galingale rhizome、 rehmannia root、 two-toothed achyranthes root; Kidney-deficiency and blood stasis:Chinese angelica、 Sichuan lovage root、 danshen root、 corydalis rhizome、 prepared liquorice root、 peach seed、 Safflower、 medicinal evodia fruit、 Motherwort Herb、 cassia bark、 morinda root、 white peony root、 dodder seed; Qi deficiency and blood stasis:milk-vetch root、 Chinese angelica、 white peony root、 cyathula root、 corydalis rhizome、 suberect spatholobus stem, Motherwort Herb、 dodder seed、 mugwort leaf、 prepared liquorice root、 nutgrass galingale rhizome; Qi and blood deficiency:white peony root、 milk-vetch root、 codonopsis root、 donkey-hide gelatin、 Chinese angelica、 white atractylodes rhizome、 Indian bread、 prepared rehmannia root、 Motherwort Herb、 combined spicebush root.3 The summary of commonly used Chinese medicine for syndrome types of primary dysmenorrhea:most of the Chinese medicine entered liver and spleen channel. The ratio of medicine entered liver channel to cold congealing and blood stasis, qi stagnation and blood stasis, kidney-deficiency and blood stasis, qi deficiency and blood stasis, qi and blood deficiency are 34%,28%,38%,38%,20%, respectively. The ratio of medicine entered spleen channel to those syndrome types are 24%, 26%,17%,23%,27%, respectively.4 The result of the summary of commonly used Chinese medicine for syndrome types of primary dysmenorrhea:the Chinese medicine for invigorate blood, rectify menstruation and relieve pain are in the majority.Conclusion:1 The common TCM syndrome differentiation:cold congealing and blood stasis, qi stagnation and blood stasis, kidney-deficiency and blood stasis, qi deficiency and blood stasis, qi and blood deficiency. The corresponding therapeutic principle:warm the channels and dissipate cold, dissolve stasis and relieve pain; rectify qi and move stagnation, dissolve stasis and relieve pain; supplement kidney and invigorate blood, dissolve stasis and relieve pain; supplement qi and nourish the blood, dissolve stasis and relieve pain; boost qi and nourish the blood, rectify menstruation and relieve pain.2 Commonly used Chinese medicine for syndrome types of primary dysmenorrhea:Cold congealing and blood stasis: Chinese angelica、Sichuan lovage root、corydalis rhizome; yanhusuo、nutgrass galingale rhizome、fennel、red peony root、white peony root、cassia bark、 flying squirrel faeces、 combined spicebush root、medicinal evodia fruit、tree peony bark; Qi stagnation and blood stasis：corydalis rhizome、Chinese angelica、red peony root、peach seed、prepared liquorice root、Sichuan lovage root、bupleurum、Safflower、 orange fruit、nutgrass galingale rhizome、 rehmannia root、two-toothed achyranthes root; Kidney-deficiency and blood stasis:Chinese angelica、Sichuan lovage root、danshen root、corydalis rhizome、prepared liquorice root、 peach seed、Safflower、 medicinal evodia fruit、Motherwort Herb、cassia bark、morinda root、 white peony root、dodder seed; Qi deficiency and blood stasis:milk-vetch root、 Chinese angelica、 white peony root、cyathula root、 corydalis rhizome、 suberect spatholobus stem、 Motherwort Herb、dodder seed、 mugwort leaf、 prepared liquorice root、 nutgrass galingale rhizome; Qi and blood deficiency:white peony root、milk-vetch root、 codonopsis root、 donkey-hide gelatin、 Chinese angelica、 white atractylodes rhizome、Indian bread、prepared rehmannia root、Motherwort Herb、combined spicebush root.3 The summary of commonly used Chinese medicine for syndrome types of primary dysmenorrhea:most of the Chinese medicine entered liver and spleen channel.4 The result of the summary of commonly used Chinese medicine for syndrome types of primary dysmenorrhea:the Chinese medicine for invigorate blood, rectify menstruation and relieve pain are in the majority.