Study On A Novel Real Time Image Collection System For Point-of-care Test

Much detection results should be identified according to color or gray scale in environmental or medical detection, such as gold nanoparticle-based immunochromatographic test or micro-array bitmap, now detection method with naked eyes or with scanner combined with computer is utilized in this kind of biomedical detection. But the results would be inaccurate when it is used for detection of high density or multi-channel data, small size can not be realized, either. It is significant to develop a micro real time imaging system on the base of this biomedical detection method combined with image processing technology. Some point-of-care testing (POCT) can be dealt using this imaging system. Until now, normal real time imaging system could be a module connected with computer, CPLD+DSP framework and CCD are adopted in the normal imaging system, it can not be utilized in POCT. In this dissertation, the author introduces a new CMOS+FPGA structure taking place of CPLD+DSP in the design of real time imaging system. The topics of this dissertation are presented as below:1. The present situation and develop direction of biomedical detection part and data processing part in POCT is presented. To improve the normal large scale imaging system in biomedical detection, an innovative design based on FPGA embedded with DSP is put forward after the comparison of all kinds of embedded imaging and processing system.2. Hardware design with modularization is put forward, including image capturing module,image processing module,Liquid Crystal Display. The layout of the PCB board has been accomplished using Cadence design software. Operating system and application software is finished by the author, especially the design of asynchronous FIFO and the function for the YUV to RGB conversion.3. Sample device is produced and passes the basic test, and is utilized in biomedical experiments. The error statistic and analysis are also presented in the dissertation. The experimental result proves that result error between this imaging system and normal system in the lab could be omitted, the cost and power consumption of the small size system is reduced.The dissertation showed that the real time imaging system has some advantages such as small size, low power consumption, excellent real time performance when it is used for dealing with image signal at same situation. This real time imaging system succeeded in building a new hardware platform for POCT device.