Studies On Synthesis, Characterization, Crystal Structures Of Nitrogen Heterocycle Ligands And Zn (Ⅱ) Complexe

It is significant in organic chemistry to study on azirine for it presents in abundance innature, and can be applied widely. Azirine with strong coordination ability and diversecoordination modes that attracts most people’s attention has been widely used in variousresearch yields, such as in drugs, pesticides, materials, catalysis. This thesis includes thefollowing five sections:The first chapter we summarized the research of synthetic methodologies of heterocyclic,oxygen heterocyclic, sulfur heterocyclic compounds and quinazoline derivatives in recentyears. And we summarized research applications of quinazoline compounds in thepharmaceutical, natural products, ion recognition aspects. Finally, the Schiiff bases complexeshave been summarized in various research area.The second chapter of this paper, we have synthesis aminoacetophenone oxime animportant intermediate compoud on previous experience. Seven quinazolines ligands havebeen synthesized by the reactions of aminoacetophenone oxime with3-pyridinaldehyde,2-thenaldehyde, furfural, piperonyl aldehyde,1,4-phthalaldehyde,3,5-dibromosalicylaldehyde,3,5-dibromosalicylaldehyde, preparing seven kinds ofquinazolines ligands, these ligands are:2-(3-pyridinaldehyde)-4-methyl-1,2-dihydroquinazoline3-oxide (HL1),2-(2-thenaldehyde)-4-methyl-1,2-dihydroquinazoline3-oxide (HL2),2-(2-furfural)-4-methyl-1,2-dihydroquinazoline3-oxide (HL3),2-(2-piperonyl aldehyde)-4-methyl-1,2-dihydroquinazoline3-oxide (HL4),2,2’-(1,4--phenyl)-di(methyl-1,2-dihydroquinazoline3-oxide)(HL5),2-(3,5-dibromo-2-hydroxyphenyl)-4-methyl-1,2-dihydroquinazoline3-oxide (HL6),2-(3,5-dichloro-2-hydroxyphenyl)-4-methyl-1,2-dihydroquinazoline3-oxide (HL7). The sevenligands have been characterized by analysis methods of solubility experiments, elementalanalysis,1H NMR. Finally, we discussed the possible reaction mechanism of producing theligands of quinazolines.The third chapter, we reported the use of the solvent evaporation under normaltemperature and pressure, producing colorless and prism single crystal ligand which is2-(3,5-dibromo-2-hydroxyphenyl)-4-methyl-1,2-dihydroquinazoline3-oxide (HL6), and usingsingle-crystal X-ray diffraction to determine the structure of their molecular structure.Moreover analyzing and descriping the crystal structure,. The crystal structure shows thatwithin the two intermolecular hydrogen bonds and the two π-π stacking interactions makingligand molecules are twisting, not face to face configuration of V shapeing and the3D layered supramolecular structure. These weak interactions between the molecules play a key role inthe structural stability of the ligand crystal.The forth chapter we have obtained unexpected yellow prismatic new crystalsZn(L8)2·CH3OH, synthesized between ligand HL7and Zn(CH3COO)22H2O reaction, useingevaporation of the solvent under normal temperature and pressure method. Then the chemicalcomposition and molecular structure determed by X-ray single crystal diffraction structureanalysis method. Finally the crystal structure and reaction mechanism between ligand of HL7and salt of Zn(CH3COO)22H2O was analyzed and described.The last chapter the π electron aromatic compounds of HAT(CN)6and the TCP havebeen synthesized. Then we tried to design and synthesis more conjugated π electronaromatic rings of2,3,6,7-tetracyano-1,4,5,8-tetraazanaphthalene and2,3,7,8-tetracyano-1,4,5,6,9,10,11-hexaazaanthracene. Explored the π electron aromatic compounds withdifferent structural configuration anion, we tried to obtain a single crystal throughvolatilization and diffusion methods, which described anion-π function mode.