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Cardiac Specific Expression Of The Gene Microarray Analysis And Gene Ontology Analysis Of Its Characteristics

Posted on:2008-10-10Degree:MasterType:Thesis
Country:ChinaCandidate:C X ZhouFull Text:PDF
GTID:2190360218455890Subject:Genetics
Abstract/Summary:PDF Full Text Request
The tissue-specific pattern of mRNA express ion can indicate importantclues about gene functions.We used two dataset to find the heart-specific genes:1. The expression of the vast majority of protein-encoding human genesand have used them to profile a panel of 79 human tissues.2. 27 genes related with heart development and cardiac hypertrophydeposited in the Cardiosignal database.We found 112 heart-specific genes(τ>0.85).Analysis of 112 heart-specific genes with 6ene Ontology revealedsignificant enrichement in 62 of 60 notes. These notes prompted the commoncharacteristic of heart-specific genes.
Keywords/Search Tags:Characteristics
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