Study On Preparation And Properties Of Novel Molecularly Imprinted Polymers

This thesis is mainly composed of the following three sections:Firstly, this study was to identify the addition of inorganic pore-forming agent (PFA) could provide an efficient avenue to significantly improve the binding capacity of molecularly imprinted nanofibers (MINs), along with slight increase of their imprinting effect and selectivity. A non-covalent imprinted composite nanofiber (MIN-PFA) with in-situ generated silica as pore-forming agent was prepared by electro-spinning with naringin (NG) as template,β-Cyclodextrin as functional monomer, hexamethylene diisocyanate as cross-linker, and poly-vinylbutyral as electro-spinning matrix. For comparison, two imprinted polymers (MIN and MIP) were prepared in absence of the PFA with or without electro-spinning employed. The binding property and selectivity were evaluated by equilibrium binding experiments. MIN-PFA exhibiting high specific binding capacity (～13.0 μmol/g), could bind 30% or 57% more naringin than MIN and MIP, respectively. The isotherm of N2 gas adsorption at 77 K also proved the PFA addition could enhance the surface area of the imprinting nanofibers.Secondly, a facile approach for sensing an emerging POPs, tris(2,3-dibromopropyl) isocyanurate (TBC) is developed, based on coupling molecularly imprinting with electro-polymerization of o-aminophenol (OAP), which is electro-active monomers containing multifunctional groups. The poly-OAP film was deposited in an OAP solution by potentiodynamic cycling of potential with and without the template (TBC) on a glassy carbon electrode. Using K3[Fe(CN)6] as an electro-active marker, the properties of the TBC imprinting electrode were investigated by differential pulse voltammetry and amperometric i-t curve. The results showed that the molecularly imprinted polymer (MIP) electrode was significantly different from the non-imprinted electrode in morphologies and electrochemical properties, and a linear relationship between the value of peak current and the TBC concentration was found in the range of 1.4×10-10～6.7×10-10mol/L and a low detection limit of 6.64×10-11mol/L for TBC determination. Moreover, the MIP electrode exhibited an excellent imprinting effect and good reproducibility (RSD=1.76%).Thirdly, Using cyclic voltammetry (CV) technique (Scan Rate is 100mV/s), poly-o-Phenylenediamine film was coated on the surface of a glassy carbon electrode in the presence of TBC which was considered as the template. Using K3[Fe(CN)6] as an electroactive marker, the electrochemical properties of the TBC sensor were investigated by CV, differential pulse voltammetry (DPV) and amperometric i-t curve (AC). The results showed that a linear relationship between the peak current and the TBC concentration was found in the range of 1.4×10-12～6.7×10-12 mol/L mol/L with a detection limit of 9.03×10-13 mol/L. mol/L)。...