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And More Mi-particle Preparation Process And Quality Standards

Posted on:2007-11-24Degree:MasterType:Thesis
Country:ChinaCandidate:D J LuFull Text:PDF
GTID:2191360185451765Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Yuxinggeng granule comes from the kangxin formula which is studiedby xiyuan hospital in Traditional Chinese medicine institute of China,combining yiqihuoxue method with western medicine medication, used totreat AMI, xinlv etc. The prescription of yuxing granule consist ofrhizoma coptidis , radix rhizoma salviae , rhizome polygonati, radixrhizoma salviae Miltiorrhizae , radix curcumae and can dramaticallydecrease the bingsilv of AMI patients down to 10% and Reduce theoccurrence of complications and Improve heart rise and Improve acutecardiac infarction patients with heart function, the role of reliable.The research include the preparation and quality standard by HPLC andTCL methods, which is based on the analysis of the prescription and activeconstituents , according to" the method of the new drugs approval" . Ofthe following major melting:Preparation: the main work is listed below.1 The crude materials were identified with TLC according to China pharmacopiea(2000edition, I), the results was satisfying.2 the quantity of water in the decocting process was studied. Prescription, rhizoma coptidis , radix codonopsis, radix paeoniae rubra prescription medicines requiring water, the side of a peony Significant indicators of the more Xingeng particles in the water extraction process studied experimental results indicate; Increase water volume for the eight times the appropriate medicines.3 Baptist high enrichment dry conditions for small research using vacuum enrichment and spray drying methods, their conditions of the study, the experimental results; Vacuum enrichment conditions for vacuum 0.06kpa temperature 60 degrees centigrade, enrichment relative to the density of 1. 15 (60℃ testing), another spray dry conditions are liquid temperature is 60 ℃. ~-175 temperature of 170 degrees centigrade into goods exports 85 temperature 80℃ centigrade, the wind volume 4, compressed air 2kg/cm25 Shaped research craft5.1 Promotion of research and usage5. 2 Zhili research methods. Conducted using different concentrations Zhili, observation Zhili effect, the results of experiments using 80% ethanol concentration Zhili, the consumption of medicinal powder 1/3 appropriateThrough this study, identified as the more Xingeng particles produced are : prescription medicines, flavors White games, Yanhusuo, angelica, mixed four flavor sma.sh into powder, a 80-eye filter and the...
Keywords/Search Tags:yuxingenkeli, Paeoniflorin, Astrgaloside IV, HPLC, TLC
PDF Full Text Request
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