Preparation And Quality Standards Of Traditional Chinese Medicine Lipid-lowering Particles Studied

Hyperlipidemia is one of familiar clinic symptoms, and so many people are tortured for getting this illness. And hyperlipidemia is one factor to induce coronary artery disease, arteriosclerosis, adiposis hepatica, diabetes and adiposis. So it's very important to find some liporegulators which are effective and atoxic. Up to the present, there are many drug researches in this domain, and Chinese herbs have lots of advantages, such as abundant medicinal herbs resource, less toxicity, and so on. In addition, Chinese herbalism which treats the illness by dialectic theoretics can receive better effect, and has huge potential in treating hyperlipidemia.The research of lipid-decreasing granule consists of following parts. Firstly, the reseach investigates the pharmacology and the clinical practice of each medicinal material in this compound. Secondly, according as the physical-chemistry character of the medicinal material, the research optimizes the best technics of decocting and depositing solution by orthogonal experiment. And in order to optimize the molding technics, the proportion of ointment to excipient, the molding temperature and the concentration of ethanol is studied, and then the praeparatum technics is determined. Thirdly, in order to effectively control the quality of this new medicine in process of production and ensure the well clinic application, the research studies the Quality standard of the medicinal material, assistant material and patent medicine. Fourthly, the elementary stabilization of preparation is also studied in order to provide a well-rational, well-stable and well-safely controlled technics. Through above-mentioned experiments, it is sure that this new Chinese medicine is suited to the larger scale productin for treating hyperlipidemia in clinic. Fifthly, pharmacology experiment is done, and the result reveals this granule's lipid-decreasing effect.