Study On The Preparation And Quality Stardard Of Juemingqingzhi Granule

Juemingqingzhi granule is a new modern compound preparation of Chinese medicine, based on the folk experienced prescription of our country trami, so as to mainly cure hyperlipidemia disease with high incidence.According to the function and indication of the formula and the properties of its chemical components, as well as their pharmacology function, the route of preparative procedure and index components were ascertained, which were chrysophanol and rutin. Guided by the contents of index components, the extract rate and so on, the research used orthogonal experiment design or signal factor method to optimum conditions of preparation, which included refluxing extraction, warm extraction, water decocting extraction, purification, condensing and drying process, granulation. The reduplicate experiments and feasible analysis were conducted under optimum operating condition. Moreover, the formula were identified by TLC, at the same time, chrysophanol and rutin, which are important physiological active components, were determined, so that the research establish the main quality control of patent medicine.In the optimum refluxing extraction condition, the transfer rate of the...