Micron Crushed Ginseng Preparation And Preliminary Evaluation

Radix et Rhizoma Ginseng Rubra products for the cultivation of Radix Ginseng by steaming the dried root and rhizome after. With nourishing vitality Fumai solid off, Qi and blood intake function. Micron red ginseng ginseng is generally prepared into 1～75μm powders, micron technology by increasing surface area of drug particles to promote the dissolution, increased bioavailability, thereby enhancing the efficacy and finally saving medicine resources.Optimization micron ginseng preparation, establishment of quality standards micron draft red ginseng; study of red ginseng powder after the powder characteristics, the impact on the effective components, and major changes of efficacy for ginseng processing product development and application of the reasonable theoretical foundation and experimental data.Single factor method of influencing factors of red ginseng micron filter. The average particle size, angle of repose, bulk density and output ratio for evaluation, determine the use of HMB-701-type knife mill for production of ginseng-micron technology for the best: The bag length 20 cm, grinding time 40 min/times, the feedstock into a single 500 g/ second. Output-micron particle size range of red ginseng between 1-35μm.Micron red ginseng initially established quality standards. Tested by laser particle size and particle size distribution was detected, the provisions of micron ginseng D50 to 25-45μm, span of 0.2-0.7; to TLC for identification, in the control medicines and location of the test sample had color in the corresponding the same spot, the color clear, no negative interference, good separation; by HPLC ginsenoside Rgl, Re, Rb1 content, and its linear range, precision, recovery and other parameters were investigated The results show that the method meet the requirements for analysis. Samples in ginsenoside Rgl, Re, Rb1's content 2.06,1.77,2.41 mg/g.Comparative investigation HPLC, ginseng powder and the micron of ginsenosides ginseng slice. The measuring results, ginseng microns in determination that under the condition of superfine powder to ginseng saponins composition. Using experimental animal models of some of micron ginseng pharmacological effects. The results showed that red ginseng in mice micron significant stress effect; on immunocompromised mice the thymus and spleen have a protective effect; could enhance the learning ability of mice promoted; preliminary safety evaluation results show that No test dose range of toxicity.