Dimetridazole Residues In Eggs

40 healthy laying hens were involved in this experiment. Objectives: To get guidance that how to use DMZ reasonably and to perfect the research system of DMZ and imidazole medicine residues through detecting the residue of DMZ and DMZOH in eggs and measuring the numbers and weight of eggs delivered by the hens. Methods: The laying hens were raised with different dosage of forage (150mg/kg,500mg/kg,1000mg/kg) mixed DMZ. Before, during and after using the forage, the weight and quantity of eggs was measured respectively, and the residues of DMZ and its metabolite DMZOH in eggs were detected through the method HP1C separately. Results: There was no difference between the numbers and weights of eggs from the laying hens raised with forage mixed DMZ and that from the control group. Additionally, the difference didn't exist in the groups raised with different dosage of forage. DMZ and DMZOH could be detected in all experimental groups during using DMZ. The contents were positive related with the dosage of DMZ and time. The remains of DMZ and DMZOH in each group decreased gradually since stopping using DMZ. And the residue of DMZOH was always more than that of DMZ. But till the ninth day after ceasing medicine, the residue of medicine decrease to 0.01ug/kg. Till the 10^th day, DMZ and DMZOH could not be found in each group. Conclusion: According the results of this experiment, DMZ and DMZOH could be found in the experimental groups within 9 days since using medicine and stop using medicine. The egg products and meat products of laying hens raised with DMZ should be sold at least 10 days later when ceasing breeding DMZ.