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The. Cyathula Quality Evaluation Studies

Posted on:2009-04-20Degree:MasterType:Thesis
Country:ChinaCandidate:D D ChenFull Text:PDF
GTID:2193360272964316Subject:Pharmacognosy
Abstract/Summary:PDF Full Text Request
Rhizoma Cyathula was the drying plant roots of Cyathula officinalis Kuan. Sweet and bitter in flavor,slightly warm in property,acting on the liver and kidney channels.It has the function of resolving the blood stasis to regulate collaterals, promoting joint movemnet,relieving stranguria by promoting diuresis.Ues in amenorrhea,arthralgia in joint,hyperkinesia,wilting of the legs,bloody urine and strangury,phlegmon,swelling and pain.It's one of the most famous trueborn drugs in Sichuan province,Rhizoma Cyathula was found in the Tang Dynasty first,after the Ming and Qing Dynasties,Many herbal books recorded the character and property flavuor of "Rhizoma Cyathula" and "Rhizoma Cyathula plant in sichuan".Pharmacological studies show that Rhizoma Cyathula improve microcirculation immunity,treate osteoporosis.Rhizoma Cyathula distributed in Sichuan,Yunnan and Guizhou,wild or cultivated.Since ancient times,Doctor in Chinese had mass in use of Rhizoma Cyathula,after the Ming and Qing dynasties,there were describtion the effectiveness and distinction of "Rhizoma Cyathula" "Rhizoma Achyranthes" in a small number herbal books.There were littler describtion and legend shape of the "Rhizoma Cyathula" in the ancient herbal books so we can not determine its original plant.《Chinese Pharmacopoeia》1963 containied the Cyathula capitata (Wall.) Moq.and the C.tomentosa Moq.as"Rhizoma Cyathula".Until the《Chinese Pharmacopoeia》1977 amended as Cyathula officinalis Kuan according to germplasm and effectiveness.now,in southwestern Sichuan and Yunnan areas,also often use the drug Cyathula capitata(Wall.) Moq. as "Rhizoma Cyathula".the root confusion.The issue of "Rhizoma Cyathula".and Cyathula capitata(Wall.) Moq.a plant morphology of identification,through the form of plant and microscopic identification of two varieties to identify and distinguish,and find common ground and differences between them.There were character identification,《Chinese Pharmacopoeia》2005 version Achyranthes-under-the-Achyranthes the quality control of a character identification,microscopic identification,ash containing examination,the acid insoluble ash,water,leaching of standards.We criteril the "Rhizoma Cyathula" quality standards through the trial study on to TLC cyasterone and ferulic acid,cyasterone and ferulic acid content as an indicator component.Initial prepared Achyranthes quality standards(Draft),and cyasterone content of not less than 0.025 percent,ferulic acid content of not less than 0.110 percent.We study the "Rhizoma Cyathula "fingerprint of the HPLC first time in this issue,establishment the "Rhizoma Cyathula" fingerprint from by screening of the experimental methods and conditions of 18 "Rhizoma Cyathula" raw drug.
Keywords/Search Tags:Quality standards, Rhizoma Cyathula, fingerprint, HPLC
PDF Full Text Request
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