Hepatitis B With Cirrhosis And Ascites, Tcm Syndrome

Objective To investigate the syndrome law of TCM in the ascites of hepatitis B cirrhosis and its correlation with the physical and chemical examination, based on the guideline of clinical epidemiology, hoping providing some reference for Chinese medicine in treatment determination based on syndrome differentiation of ascites in hepatocirrhosis.Methods Firstly, collect the clinical symptoms of TCM of ascites of hepatitis B cirrhosis based on the Summary of hepatitis B liver cirrhosis of Chinese epidemiological literature, then establish Initially a clinical epidemiological survey questionnaire, at last determine the required clinical symptoms of the survey questionnaire item pool in TCM, and the corresponding classification of quantitative criteria symptoms by relevant expert advice and feasibility analysis, repeated discussions and seminars and clinical research guidelines.The subject were collected in 11 hospitals, decompensated cirrhosis TCM Syndrome 357 cases of clinical data, collect the cases based on the inclusion criteria, observe the cases by the observed content, fill the form of the Chinese medicine syndrome of hepatitis B cirrhosis in decompensated stage, enty the data of the case to the computer and analyze the data after the observation.Study the feature of the syndrome of TCM in the ascites of hepatitis B cirrhosis by the method of facter analysis.Result1. Characteristic of the Symptom The main syndrome of the case is Liver and spleen, kidney is also important, which is consistent with the reported disease of Hepatitis B cirrhosis the location in the liver, spleen and kidney, also consistent with the clinical practice.2. Characteristic of the Pathogenesis Visceral lesions is liver, spleen and kidney. Five Pathogenesis:Qi (Qi stagnation), Fire (liver fire and fire deficiency), wet/water (cold wet and warm wet), blood stasis, deficiency (Qi and Yin deficiency). The five factors influence and interact each other.3. Characteristic of the syndrome The single syndromes (41.45%) and the compound syndromes (35.65%) cross each other, but compound syndromes account for a large proportion, which note that the syndromes are complicated. The Proportion between the deficiency and excess syndromes:the deficiency is 34.72%, the excess is 10.92%, the compound of deficiency and excess is 31.37%, that is to say, the syndromes are complicated.4.The relevence between syndrome and chemical indicators Total bilirubin, serum albumin, white blood cell count, hemoglobin, platelet count, prothrombin time and the spleen weight on cirrhosis ascites influence the distribution of the syndrome characteristics.Conclusion The pathogenesis of this disease can be summarized as the Qi, fire, wet/water and stasis,which is mixed with each other infestation. The feature of this disease is that the compound deficiency and excess is main, the principal pathogenesis is Qi stagnation and, spleen and kidney deficiency, water retention in belly. The syndromes of the disease show that some syndromes performance at the same time, deficiency and excess mixes each other, so we should use every methods to cure the ascites of hepatitis B cirrhosis and not rigidly adhere to a law.