Clinical Efficacy Of Tone The Liver Spleen And Kidney And The Main Group The Treatment Of Ascites Due To Cirrhosis

Objective:To observe the clinical curative effect and blight of the formula which primarily be composed of adjusting the liver,invigorating the spleen and nourishing the kidney to treat liver cirrhosis ascites,objectively evaluates its validity and security of treating liver cirrhosis ascites, and discusses its function mechanism initially,to provide the beneficial reference for clinical treating liver cirrhosis ascites.Methods:All cases of illness which admited to the liver branch ward in the first affiliated hospital of Hubei TCM College were from May,2007 to April, 2008,conformed to the diagnosis standard of liver cirrhosis ascites, altogether 60 examples,divided into the treatment group and the control group stochastically.The treatment group 30 examples,used the formula coordinating conventional western medicine to treat just right for the illness;the control group 30 examples,used the conventional western medicine to treat just right for the illness.When necessity two groups gived the abdominal puncture to extract ascites for treatment of reducing pressure.Two weeks were a treatment course,altogether two treatment courses.Recorded the main symptoms,the symptom(distension of the abdomen, few urine,asthenia,accepts difference,jaundice,edema of the double lower limbs),the liver function,the body weight,the abdomen encircle, the abdomen B ultrasonic inspection(spleen thickness,portal vein and spleen vein width)a time respectively before and after the treatment and the complication situation after the treatment,and monitored the 24h amount of urine,according to the corresponding standard of diagnosing and treating,maked the curative effect appraisal;observed the general medical examination for the body(for example T,P,R,BP),blood routine test,urine routine test,stool routine test and kidney function,the electrocardiogram and untoward effect a time respectively before and after the treatment,maked the secure appraisal.After the observation had ended,possessed all the data to carry on the statistical analysis,all statistical test used the two-sided test. The measurement data used the mean value±standard deviation((?)±s) to carry on the statistical description,the measurement date used the T-test,the counting date used the chi-square test.P＞0.05 had the non-significance difference,P＜0.05 had the significance difference,P＜0.01 had the unusual significance difference.Results:1 Total effect comparison:Treatment group total efficient 93.3%,control group total efficient 70.0%,two groups have the significance difference(P＜0.05),indicating that the treatment group have a better clinical total effect for reating liver cirrhosis ascites.2 Two groups of patients main symptoms,symptom improvement comparison: The treatment group symptoms,symptom improvement are obvious,surpasses the control group,the statistical analysis has the significance difference(P＜0.05);the comparison before and after treatment the treatment group and the control group all have the significance difference (P＜0.05).3 Two groups of patients liver functions,zymoplasm activity comparison:The treatment group liver function,the zymoplasm activity improvement is obvious,surpasses the control group,the statistical analysis has the significance difference(P＜0.05);the comparison before and after treatment the treatment group and the control group all have the significance difference(P＜0.05).4 Two groups of patients body weights,abdomen encircle,the average 24h amount of urine comparison:Before and after treatment the treatment group body weight,abdomen encircles,the average 24h amount of urine change obviously,surpasses the control group,the statistical analysis has the significance difference(P＜0.05);the comparison before and after treatment the treatment group has the significance difference(P＜0.05); the average 24h amount of urine comparison before and after treatment the control group has the significance difference(P＜0.05),but body weight, abdomen encircle change not obviously,non-significance difference (P＞0.05).5 Two groups of patients abdomen Bultrasonic(spleen thickness,portal vein and spleen vein width)comparison:Before and after treatment the treatment group abdomen Bultrasonic(spleen thickness,portal vein and the spleen vein width)changes obviously,surpasses the control group, has the unusual significance difference(P＜0.01);the comparison before and after treatment the treatment group has the significance difference (P＜0.05);the comparison before and after treatment the control group treats has the non-significance difference(P＞0.05).6 After treatment two groups of patients the complication situation comparison:After treatment two groups of patients the complication examples,the treatment group is fewer obviously than the control group, has the significance difference(P＜0.05).7 Security comparisons:After treatment two groups of patients the general medical examination for the body,blood routine test,urine routine test,stool routine test and kidney function,electrocardiogram examination all not obviously change;in the course of treatment and after treatment,also no untoward effect appears,indicating that the formula is safe and has no obvious poisonous side effect for treating liver cirrhosis ascites.Conclusion:The clinical observation indicate that:The treatment group using the formula to treat liver cirrhosis ascites is curative which be affirmed, improving patient symptoms,symptom,liver function and so on surpasses the control group,also reduces complication occurrence,reduces the patient pain,enhances the quality of life which the patient to survive, and security,the economy simultaneously,provides the beneficial reference for us to treate liver cirrhosis ascites.