.116 Patients With Type 2 Diabetic Patients With Depression Tcm Syndromes Characteristics And Clinical Observations, And Blood Glucose

Diabetes is based -- life activities metabolic state with metabolic regulation turbulence, the important hormones -- insulin production and function of chronic performance obstacles and metabolic disease. Diabetes as a chronic medical problem for patients has brought influence, easy cause patients appear all sorts of psychological barriers, especially in depression negative temper common. And depression and diabetes also bring various negative effects, give the patients themselves, family and the whole society bring huge burden. Relations with diabetes and psychological factor, whether in the pathogenesis, clinical manifestations of prevention treatment gain more and more attentions.Objective:this topic in Chinese medicine theory is under the guidance of diabetes comorbid depression, research, statistical patients depression through the study, hope incidence of diabetes comorbid depression explore characteristics of the traditional Chinese medicine syndrome to treat diabetes comorbid depression provides guidance; And analyze the diabetes comorbid depression) with the relationship between blood glucose control level, in order to improve the physicians to diabetes comorbid depression the importance of understanding of depression, enhance the ability of the identification, diagnosis and take positive related intervention measures to improve life quality and improve diabetes patients with the purpose of the health status. This thesis includes literature review and clinical research two parts.Comorbid diabetes were introduced emphatically reviewed, including depression in TCM medicine for depression comorbid depression cognition, diabetes TCM pathogenesis, syndrome differentiations, treatment and regulating; Modern medicine for diabetes and summarizes the research progress of comorbid depression, mainly from modern medicine for melancholy comorbid diabetes epidemiology, etiology and pathogenesis of understanding, diabetes and depression relationship, clinical features and diagnosis, diabetes comorbid psychological barrier hazard factors, diabetes comorbid depression treatment, etc.Methods:clinical studies to 116 patients with diabetes was part of the investigation, all cases were 2010 July to March 2011 doctor in our endocrine division hospital patients. According to Hamilton depression rating scale (HAMD) and diabetes clinical observation, collecting and watch cases questionnaire. Generally include name, sex, age, height, weight, duration, past medical history, treatment method etc. Laboratory index includes:fasting plasma glucose (FPG) and 2-hr plasma glucose (2hPG), glycated hemoglobin (HbAlC), also include diabetic peripheral neuropathy, diabetic retinopathy, diabetic nephropathy complications such information. Record symptoms, and coating on the tongue, such as pulse string of TCM syndrome. Data using statistical software application SAS medicine, measurement data statistics and analysis, said by using standard mean+t test, count by chi-square testResults:1.116 cases were group of qi and Yin and diabetes, type two empty, with an incidence of 37 cases 31.90%; Followed by> humid and stomach of spleen> context stasis resistance trapped type. The diabetes comorbid depression is 31 cases for 26.72%, incidence of a disease. Diabetes mellitus and depression group and most, for stomach 9 cases, accounting for 27.58%; Followed by two qi and Yin deficiency syndrome 7 cases, accounting for for 22.58%, blood stasis contexts, hot and humid trapped spleen and Yin's hotness card for 4 cases, each 12.90%, Yin and Yang of two empty for 3 cases, accounting for 9.67%. Two groups of syndromes constitute than no obvious difference (p<0.05).Different syndromes and card group stomach for is 42.86%, highest incidence of depression. Qi and Yin deficiency syndrome and two with two groups of depression syndrome stomach incidence rates have difference (p<0.05), and higher than the stomach qi and Yin deficiency syndrome; two and the rest of the syndrome binary comparison differences between incidence was not statistically significant (p>0.05).2.Diabetes with depression and no depression group compared to two groups of fasting blood glucose, blood glucose 2-hr no difference between the two groups, glycosylated hemoglobin value difference have statistical significance, depression group below the depression group level; After Spearman rank and related inspection, r =-0.28, p=0.0021; HbAlC level with negative correlation between depression; And 2hPG and depression degree, FPG for (p> 0.05 found correlation.2hPG of HbAlC, FPG, single factor unconditional Logistic regression, HbAlC, FPG HbAlC into regression equation with whether depression, negative correlation with disease pathogenesis, FPG positively related to whether depression.