VDT Working Women In Peripheral Blood Lymphocyte Micronucleus In Sister Chromatid Exchange, And Fluffy Study On Micronucleus

Objective To investigate the effects of exposure to video display terminals (VDTs) on DNA in peripheral blood lymphcytes from women in early pregnancy. Methods Peripheral blood lymphcytes from 30 women of childbearing age working with VDTs were cultured and conducted sister chromatid exchange (SCE) and micronucleus analysis. 20 women in early pregnancy using VDTs were randomly selected. Micronucleus analysis was carried out in these women's villous cells. Results (1) There is no significant difference in incidence of SCE between study group and the control's. (6.8917±1.6846 per cell versus 6.4650±1.5194 per cell),(P>0.05).(2) The expression of micronucleus in peripheral blood lymphcytes in study group was 4.0667±0.8066‰.It was 3.6833±0.8251‰ in the control's. There was no statistically significant difference(P>0.05). (3) There was significant difference in expression of micronucleus in villous cells. (1.0504 ±0.6262‰ versus 0.6253±0.5098‰), (P<0.05).Conclusions Although electromagnetic fields emitted by VDTs can't cause obvious DNA damage in women using VDTs, they may cause DNA damage in VDT users' embryo. Whether use of VDTs can result in adverse pregnancy outcomes needs further investigation.