| Objective: To study the effects and possible mechanism of YSSX pill in treating CHD LVDD. Methods: 70 cases are divided into two groups randomly. The treatment group (40 cases) are treated with YSSX pill, lOg, 3 times a day, while the control group (30 cases) treated with Diltiazem, 3 0mg, 3 times a day. 4 weeks is a therapeutic period. The effects of cardiac function, angina, electro-cardio-gram (ECG) and symptom are observed between the two groups. The changs of diastolic function of left ventricle (E apexes-. A apexes-. A/E AC-. DC-. EATDT 1/3FF). blood-fat and hemodynamics indication are also compared between before and after therapy. Results: YSSX pill can obviously improve the cardiac function (P<0.05) and diastolic function of left ventricle indication (P<0.O5orO.0 1), the symptom of angina (P<0.05) and ECG. The total effective rate of improving symptoms of treatment group is 90% (P<0.0l). The YSSX pill can significantly ameliorate the symptoms such as feeling of oppression in the chest, palpitation, fatigue, frequent micturition (P<0.05), etc. and can depress blood-fat and hemodynamics (P<0.05 or 0.01), etc. There is significant difference between the two groups. Conclusion: The mechanism of CHD LVDD is blood stasis due to deficiency of the kidney and congestion of fluid-retention. It shows that tonifying the kidney and promoting blood circulation and inducing diuresis is an effective therapeutic method of CHD LVDD. it is of great value to guide the clinical practice. Theme words: Yi Shen Shu Xin pill (YSSX pill);Coronary atherosclerotic heart disease left ventricular diastolic dysfunction (Cl-ID LVDD);Blood stasis due to deficiency of the kidney;congestion of fluid-retention;Clinical study. |
PDF Full Text Request