Decade After Universal Salt Iodization Periodate Ward Condition Survey

Objectives: To master the effect of high iodine on people by investigating the disease state after ten years of universal salt iodization (USI) in Ying County, So that finding the suitable prevention and treatment measures. Method: Field epidemiology survey was applied in high-iodine areas of Ying County. Water iodine concentration determined by arsenic-cerium catalytic spectrophotometry. Thyroid of children aged 8-10 years was diagnosed by palpating and diagnostic criteria was GB16004-1995(Diagnostic and classificatory criteria of endemic goiter).Urinary iodine was determined by arsenic-cerium catalytic spectrophotometry. The children's IQ values were measured by the Combined Raven's s Test (CRT-C2). Iodined salt was determined by direct titration. Results: Five hundred and sixty-eight water samples were collected and the median of water iodine was above 150^g/L in 6 towns. The lowest concentration of water iodine was 0.4g/L and the highest concentration of water iodine was 875.4g/L .Eighty-eight cases of I?goiter and 1 case of II0 goiter were diagnosed among 1238 children aged 8-10 years in 6 high-iodine towns and the goiter rate was 7.19%, which was significantly higher than that before adopting USI (x 2=3.99, P <0.05). The goiter rate of different sex did not have significant different ( x2=0.0443, P>0.05) . The goiter rate of different-aged children was significantly different ( x2= 11. 33 , v=2 , P<0. 01) and the goiter rate of 8 years group was lower than that of 10 years group ( x 2=11.10, P <0.05 ). The median of urinary iodine was 528.31g/L, and was significantly higher than that before adopting USI (u=3.68,P<0.01). The median of urinary iodine of different sex didn't have different (u=0. 56, P>0. 05) . The median of urinary iodine of different-aged group was significantly different (H=8. 58, v=2, P <0. 05) .The highest urinary iodine concentration was 2681.3g/L and the lowest was 12.6g/L. The average of IQ was 108.4 in villages with water iodine above 150g/L and was 107.7 in villages with water below 150g/L, and they did not have significant different (t=0. 58, P>0.05). The average of the salt iodine concentration was within the scope of 20~50mg/kg in 6 towns. The cover rate of iodined salt was about 90%. Conclusion: The urinary iodine concentration was increased after adding iodine to table salt in high iodine areas, which results in the goiter and does not obviously affect IQ. So it must stop supplying iodized salt in high-iodine areas.