Moso National Drug Research

Mosuo pelope inhabited Lugu lake where march with Yunnan province and Sichuan province for generations. Mosuo pelope is one branch of Naxi nationality in Yunnan province, and another branch of Mongol in Sichuan province respectively. Mosuo pelope hold primitive matrilineal-clannish culture as yet. Few researches have been conducted on traditional medicine of Mosuo pelope, so we conducted an ethnopharmacological investigation into the study of the traditional medical knowledge and traditional herbal medicine of Mosuo pelope. Anthropology, ethnobotany, pharmacognosy, pharmacology, pharmaceutical chemistry were used in this study. Through evaluating potential value, we can screen out the best herbal medicine to evaluate the quality. The research investigated and recorded traditional medical knowledge, promoted sustainable development of new drugs and wellness products.The results of this study are concluded as follows:1. Common ailment of Mosuo pelope associated with geographical environment and custom. Traditional medicine primary is medical treatment.The characteristic of traditional medicine of Mosuo is still in the witch-physic primitive stage. Mosuo medicine is affected by multinational culture.Religion plays an important part in the course of treatment. Taditional medicine is likely to prediction of a person's luck in a given year.2. It was founded that the traditional herbal medicine are from 69 family 126 genus 140 species plants by botanical catalogue. The way of using medicine is of national feature. Through statistical methods, Prinsepia utilis Royle etc has potential value of exploitation on the development of the new drug. So the study futher to investigate and sum up applied history, research status quo, folk and national situation of P. utilis.3. Associated with literature and sustainable development, we choose the leaf of P. utilis to study. In view of officinal methods of various nation, me research adopted anti- inflammatory experiment to screen out effective fraction. The effective components of P. utilis have been carried out, and the chemical components have been separated in many ways. Six components were from the effective fraction (including impregnant part of ethyl acetate and n-butanol). Adopted the spectrum analysis and the literature information, chemical structures of 4 components have been identified, which are n-tetratrialontanol, ursolic acid, rutin and isorhamnetin-3-O-β-D-rutinoside, the others are waxiness and unknown components.They are first found out from P. utilis. Quantitative and qualitative analysis of ursolic acid were measured by HPLC. Quantitative analysis of three flavones (including isorhamnetin, quercetin and kaemferin) were measured by HPLC. The study set up quality standard of P. utilis primarily.