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Chlorine Flutter Research, Quality Control Of Hemp Nasal Drops

Posted on:2007-02-10Degree:MasterType:Thesis
Country:ChinaCandidate:H ZhangFull Text:PDF
GTID:2204360218456820Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
This text with the hospital product chlorine rushes toward a nose of Lupuma liquid as object, studying its quantity control method. Study its discriminate, check and measurement of content. The chemical methods that uses to discriminate in the hospital inner part win to reserve, then increases new method. The new method is by latest medical dictionary for foundation, and do appropriate changes, adopt the thin layer method to discrimin-ate three kinds of live compositions respectively. Chloromyce-tin launches the condition as chloroform-methyl alcohol(95:5), Chlorphenamine Maleate launches the condition as Acetic acid B ester—Methyl alcohol—parse Acetic acid (5:3:2), Ephedrine Hydrochloride launches the condition as Chloroform-Methyl alcohol—Thick ammonia (20:5:0.5).The result of launching is obvious and dependable.According to the medical dictionary provision we check the quantity difference of product pack, the appearance, the pH, the microorganism limit and the heavy metals, then do capa-city provision. Among them the quantity difference of pack is±10%, the appearance check should be clarify and have no the miscellaneous quality to precipitate, the pH is between 4.5 to 6.5.1n the microorganism limit check germs number should not over 10000/ml, the number of fungi and yeast stain should be not over 100/ml, and can not check an E. coli. The content of heavy metals is not over 10 ppm.In measurement of content we measurese the content of Chloromycetin in the 276nm and 244nm, then measurese the content of Chlorphenamine Maleate in 263nm and 292 by dual-wavelength spectrophotometry. Average rates of recovery are 99.86% all, but the RSD are 1.04% and 1.36%.But Ephedrine Hydrochloride measures with the chemical titration method of the medical dictionary.
Keywords/Search Tags:Lupuma, discriminate, check, measurement of content, dual-wavelength spectrophotometry
PDF Full Text Request
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