Renal Failure Mixture Qingrejiedu The Enema Treatment Of Diabetic Nephropathy Iv Clinical Research

Objective:To study treatment effect of Shenshuai Mixture integrated heat-cleating,detoxication and enema liquid treating patients with diabetic nephropathy inⅣphaseand explore the probable mechanism.Methods:The 66 patients diagnosed the type of both Qi-Yin deficiency of Kidney-Spleenin diabetic nephropathy inⅣphase and their Scr in range of 400～530umol/L wereequally divided into the treatment group and the control group (treated by MedicinalCharcoal Tablets). All patients were treated by basic methods. In addition, the patientsin treatment group were treated by shenshuai Mixture integratedheat-clearing ,detoxication and enema liquid, while the patients in control group tookMedicinal Charcoal Tablets. The period of treatment was 8 weeks. The indexesincluding HbA1c,TG,TC,LDL,24 hours urinary protein quantity(24hu-TP,pro),Scr,Ccr and so on were measured before and after treatment. The clinic symptomswere recorded and analyzed.Results:(1) In term of efficiency, the treatment was 84.8% and the control was 60.6%.By tested, the difference in two groups was obvious, so P＜0.05.(2) In term of clinic symptoms integral, the integrals in two groups wereimproved after treatment. By tested, the difference had statistical significance incontrast of before treatment (P＜0.05). After treatment the difference in two groupswas obvious (P＜0.05).(3) After treatment, the treatment group could decrease HbA1c,TG,TC,LDLmarkedly ,the differences were obvious (P＜0.05). The control group also couldimprove HbA1c,TG,TC,LDL.But there were no significant difference(P＞0.05). Bytested, The difference in two groups was also obvious after treatment (P＜0.05).(4) shenshuai Mixture integrated heat-clearing, detoxication and enema liquidcould improve Pro,BUN,Scr and Ccr .The differences were obvious (P＜0.05). Thecontrol group also could improve BUN,Scr and Ccr distinctly, except Pro. The differences were also obvious (P＜0.05). By tested, The difference in two groups wasalso obvious after treatment (P＜0.05).Conclusion:It can obviously drop serum creatinine, decrease urinary protein quantity,accelerate fat metabolism,increase toxin expelling from bodies,protect residual renalfunction,improve clinical symptoms and delay the progress of renal failure bytreatment of Shenshuai Mixture integrated heat-cleating, detoxication and enemaliquid, so it can improve the quality of life of patients.