Remove Turbid Phlegm Treatment Of Angina Pectoris Clinical Observation Of 60 Cases

OBJECTIVE:To observe the clinical effects of treatment for curing the angina pectoris (belonging to phlegm stagnation TCM differienting) by taking advantage of the Chinese medicine called supplemented Major Bupleurum capsule,to know these security of the medicine.METHOD:to adopt the way of random, both-blindness, controll. First to selected the angina pectoris (belongingto phlegm stagnation TCM differienting) sufferers who have the right of knowing the inside story as research objects depending on the standard of joining case. After subscribe the agreeing letter, the objects are divided into the treated or comparison group by random. Before they accept the curing medicine, the objects should have medical examine. The investigate score the Chinese medicine symptom and record the examine results in CRF. Second:To give the medicine to the research objects according to the following means. The sufferers in treated group:supplemented Major Bupleurum capsule(chinese thorowax root,rhubarb,baical skullcap root,peony root, pinellia tuber,fresh ginger, immature orange fruit,Chinese dates,salvia), 0.4g/capsule, administered after 30 mins following meal, 4 capsules/time, 3 times/day. The sufferers in comparison group: xin'an capsule made by chengdu yong'an medical corproration, lot number : Z19983077, contains total flavonoids 80mg/capsule, administered after 30 mins following meal, 3 capsules/time, 3 times/day. One treatment course is 4 weeks. Except the unusual instance takeplace, the course is not ceased. During the period of this research, every medicine which can cure angina pectoris is prohibited to use. Third:The clinical symptoms, curative effect guideline, security guide line should be recorded in CRF, when the second weekend and theend of the test. Every bad affair should be recorded depending on the fact. The research should be ceased, whenever the seriousbad affair occurs. At last, To analyze the data in CRF according to SPSS10.0 statistic softwarein order to get the result of the clinical observation.RESULTS:The two groups have familiar effect, the treated group general effect rate is 93.3%. Comparedwith thecomparison group which general effect rate is 90.0%, it dose not have significant excellence (P>0.05). On theaspect of improving ECG, the general effect rate of the treated group is 53.3%; the comparison group is 50.0%. The effects of both groups have no statistical difference on ECG (P>0.05).On the aspect of improving Chinese medical symptoms,the general effect of the treated group is 96.7%,the comparison group is 93.3%.The effects of both groups have no statistical difference on Chinese medical symptoms (P>0.05).On the aspect of the ceasing and decreasing rate of Glonoin, the general effect of the treated group is 93.3%, the comparison group is 88.8%. The effects of both groups have no statistical difference on the ceasing and decreasing rate of Glonoin (P>0.05).On the aspect of reducing the blood-fat,the general effect of the treated group is 86.7% ,the comparison group is 83.3%.The effects of both groups have no statistical difference on reducing the blood-fat(P>0.05).During the whole course of the test,the bad affair never happened.The medicine has good security.CONCLUSION:supplemented Major Bupleurum capsule has remarkable effects on the angina pectoris and has good security. Compaired with xin'an capsule, it does not have remarkable merit.The effect of supplemented Major Bupleurum capsule is equal to or excel the effect of xin'an capsule.