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Due To The Banxiaxiexin Tang Duishun Platinum Rabbit Vasoactive Peptide, Substance P Receptor Research

Posted on:2010-10-10Degree:MasterType:Thesis
Country:ChinaCandidate:F WangFull Text:PDF
GTID:2204360278954448Subject:Traditional Medical Formulae
Abstract/Summary:PDF Full Text Request
Objective:Take the Chinese medicine theory as the instruction, after studying cancer chemotherapy, the gastro-intestinal tract response's accurate mechanism, lays the foundation for the clinical promoted application. The disgusting vomit which causes through the Chinese medicine fundamental research chemotherapy governs the law effectively. And unifies the modern science frontier technology, is pleased the local ruffian under for the digestive tract tumor common symptom to be full, the vomit, disgusting, the diarrhea and so on standard governs the law and the theory provides the objective basis.Methods:Uses the animal experimentation method, selects healthy domestic rabbit 32, female and male does not arrest, body weight 1.7-2.5kg. Uses (DDP) duplicates the domestic rabbit chemotherapy after the platinum gastro-intestinal tract response model. Creates symptom and so on domestic rabbit obvious anorexia taste damage pathology models. By determined that the pinellia flows swiftly heart Tang Duishun the platinum to send the domestic rabbit digestive tract response the multi-target pharmacodynamics mechanism.Results:This research through the immuno-chemistry constitutive law to gastrointestinal hormone's determination and the general observation (including feed, water volume, body weight, outward appearance Pi Se, active situation), showed the pinellia flows swiftly the heart soup after the domestic rabbit chemotherapy the gastro-intestinal tract responded that has the positive role. Surpasses the western medicine glass fine jade. Regarding next step continues to conduct the clinical research to have the guiding sense.Conclusion:The banxiaxiexin decoction swiftly the heart soup is clinical commonly used, has one of conciliatory function ancient Chinese medical classics. Through flows swiftly the disgusting vomitive mechanism research result which to the pinellia the heart soup treatment chemotherapy causes. The banxiaxiexin decoction swiftly the heart soup to be possible to enhance the gastrin, the blood vessel active peptide content effectively, may cause the P material the level drop. Thus carries on the bidirectional adjustment to the gastro-intestinal tract. Has the obvious therapeutic action regarding the chemotherapy result domestic rabbit disgusting vomit.
Keywords/Search Tags:banxiaxiexin decoction, Gastro-intestinal tract response, DDP, Gastrointestinal hormone
PDF Full Text Request
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