Ultrafine Assisted Extraction And Conventional Extraction Angelica Ferulic Acid Comparative Study

Superfine grinding as a new technology, has been widely used in various fields. At present, the technology of superfine grinding combined with conventional extraction is still limited in laboratory exploration in our country. In this paper, the comparisons of the surface properties of superfine powder and coarse powder, and the extraction efficiency of ferulic acid from Angelica sinensis by ultrafine and conventional extraction have been contrasted. The process conditions of extracting Angelica sinensis ferulic acid by ultrafine auxiliary extraction have been also optimized. The results can provide experimental references for the applicability of ultrafine auxiliary extraction technology on the extraction of active principle.The comparisons of particle size and surface structures between superfine powder and coarse powder have been made using the laser particle size analyzer and electron microscope. Under various extraction conditions, the contrast of content of Angelica sinensis in superfine powder and coarse powder was studied by single-factor experiment. In addition, the extraction conditions of Angelica sinensis ferulic acid by ultrafine auxiliary extraction were optimized according to the orthogonal Experiment. Under the same condition, the extraction efficiencies of Angelica sinensis ferulic acid by ultrafine auxiliary extraction and conventional extraction were also studied.The results shows that the particle size of Angelica sinensis of superfine powder is obviously smaller and more uniform than that of coarse powder. The surface of Angelica sinensis of superfine powder appears roughness. The ultrafine auxiliary extraction is better than the conventional extraction under different conditions. When the ethanol solution is 80%, solid liquid ratio is 1:20, extraction time is 1 hour, the extraction efficiency of ferulic acid averages 0.0256% by ultrafine auxiliary extraction, which is twice as much as that by conventional extracrion. As a means of extracting ferulic acid from Angelica sinensis, ultrafine auxiliary extraction technology is superior to the conventional extraction technology in terms of time savings and dissolution rate improvement.