Fabrication And Characterization Of Hydroxyapatite Nanomaterials

The main ingredients of skeleton and teeth of human are similar with chemical composition of hydroxyapatite, and therefore, researchers pay more attention to it. With the successful synthesis of hydroxyapatite, people also realize that it has better biocompatibility and bioactivity, which leads bone to grow up. It can combine with bones and therefore it is publicly called as good substitute materials for bone modification. Nanomaterials have the characteristics of small size and big surface area, which insure its better properties. If rare earth ions are incorporated into hydroxyapatite, it will play an important part in biological tracer. Thence, it will be an important research subject of good biological application to fabricate hydroxyapatite nanomaterials.In this dissertation, at the different temperature conditions, using CaCO3 and NH4H2PO4 as starting materials, hydroxyapatite nanorods were prepared via hydrothermal method using CTAB as a template. Hydroxyapatite naonorods were prepared via hydrothermal method using both CTAB and EDTA as templates. Europium-doped and terbium-doped hydroxyapatite nanorods were prepared via hydrothermal method using EDTA as a template. In addition, rod-shaped hydroxyapatite. Europium-doped and terbium-doped hydroxyapatite thin membranes were prepared by electrospinning using Ca(CH3COO)2·H2O, H3PO4, PVP and DMF as main starting materials. The samples were systematically characterized by XRD, FESEM. EDS, FTIR, Fluorescence, etc. The results show that Europium-doped and terbium-doped hydroxyapatite naonorods have better fluorescence properties without any biological toxicity, which can be used as biological tracer. Some significant results were achieved, and solid foundations were built for the future study of hydroxyapatite nanomaterials.