Of The The S. Mussotii And Halenia The Ethanol Extract Of Mouse Hypolipidemic Research

In this paper, the wild plants in Western Qinghai-Tibet Plateau endemic Swertia and Halenia of wild species of plant alcohol extracts on mouse model of hyperlipidemia lipid-lowering effect. Tibetan medicinal plants through research, analysis and comparison of results showed that: Swertia Sichuan, Halenia the ethanol extract had significant lipid-lowering effect. The results are as follows:Positive test group western Swertia and Halenia the low dose group, middle dose group and high dose groups can significantly reduce the fat model serum total cholesterol level, the former decreased by about 37%, 51%, 50 % And 70%; the latter decreased by about 37%, 31%, 44% and 29%.Positive test group western Swertia and Halenia low dose group, middle dose group and high dose groups can significantly reduce serum triglyceride levels of fat model, the former decreased by about 36%, 50%, 24 % And 12%, lowering triglycerides showed the effectiveness of the increase with the dose reduced; the latter decreased by about 36%, 28%, 39% and 52%, lowering triglycerides showed the effectiveness of the increase with the dose And enhanced.Positive test group western Swertia and Halenia low dose group, middle dose group and high dose groups can improve the lipid model of high-density lipoprotein cholesterol serum levels, the former increased by about 19%, 5%, 12% and 14%, compared with the model of S. mussotii only the high dose group and the experimental group showed a positive significant (p <0.05) and highly significant (p <0.01); the latter were increased by about 19%, 3% , 6% and 6%, compared with the model group showed only a positive test was significant (p <0.01).Positive test group western Swertia and Halenia low dose group, middle dose group and high dose group model can reduce the fat levels of serum low-density lipoprotein cholesterol, the former were about 36%, 12%, 18% and 33 %, lower density lipoprotein show the effectiveness of the increase with the dose reduced; the latter decreased by about 36%, 35%, 24% and 44%, reducing the effectiveness of HDL increased with the dose demonstrated to show reduced LDL decreased first and then increases the effectiveness.