The Organic Iodine Analysis After Ganoderma Lucidum Richening Inorganic Iodine And The Study Of Salt Mixed With Ganoderma Lucidum Powder Containing Organic Iodine

Ganoderma lucidum is a famous and precious Traditional Chinese medicinal materials, Ganoderma lucidum contains many kinds of essential amino acid, organic acid, Ganoderma lucidum polysaccharide (GLP), and so on. These subtances can enhance the immune power of organism. May be used as antineoplastic drug in its clinical application, Polysaccharide of Ganoderma lucidum is used to cure cardiovascular disease such as hypertension and coronary heart disease, caused by Hyperlipemia and High Blood Fat.Iodine is a trace element which was necessary for human health, Iodine deficiency will result in enlarged thyroid gland and endemic cretinism. Now the channel of iodine supplementation to body is by eating salt of iodine addition mainly, in which the mode of the existence of iodine is inorganic iodine. As opposed to inorganic iodine, organic iodine shows its great superiority in effect of supplying iodine.Ganoderma lucidum also have the function of enriching trace element-iodine, by liquid fermentation, Ganoderma lucidum mycelium can concert inorganic iodine(KI) to organic iodine. The dried product of Ganoderma lucidum mycelium which enrich to contain organic iodine may be made into foods could supply iodine. Which may realize both medicinal value and supplement iodine of Ganoderma lucidum.Using the test of single factor, study the effect on biomass of Ganoderma lucidum which grow in the iodine-containing culture medium composed of different carbon sources, different nitrogen sources,addition of KI,liquid strain quantity of inoculation. According to the single-factor experimental results, conduct an orthogonal experiment and the best combination of medium of liquid fermenting the Ganodorma lucidum mycelium enriching iodine was obtained, It is soybean flour2%, Sucrose2%, KH2PO40.15%, MgSO40.1%, the addition amount of KI is0.3%,The most economically inoculation number is10%, the cultural temperature is25℃,shaker rotate speed is150r/min. As above cultural condition, carry out submerged liquid culture, measure the pH value and determine the dissolved oxygen content of the culture medium and the biomass, reach a conclusion that the biomass of Ganodorma lucidum mycelium was most when submerged liquid cultured about36-48hours.Analysis is made on the compounds of iodine in the Ganodorma lucidum mycelium accumulating iodine, first the dry goods was alkaline hydrolyzed at110℃, the hydrolysate was carry out by solid phase extraction, the extracted liquid was determined using Liquid Chromatography Tandem Mass Spectrometry, Through determinating analysis, we couldn't confirm there were some tyrosine with iodine in Ganodorma lucidum mycelium accumulating iodine..After liquid fermentation and dried, the Ganodorma lucidum mycelium accumulating iodine was made into powder. And mixed with salt, at last was process into salt containing Ganodorma lucidum mycelium accumulating iodine, achieve change from experiment to Industrialized Production.