Serum NSE Level And Chinese Medicine Therapy And Cerebral Hemorrhage Modelrats Critical Blood Loss Was The Relevance Of The Best

Purpose: The issue that is on this basis of"85"by Dr. Ren Jixue, further to the Chinese medicine treatment of cerebral hemorrhage the best amount of bleeding for acute research. Determination in different amount of bleeding of the NSE, explore its relationship with brain damage and amount of bleeding relations with a view to be able to determine the Chinese medicine treatment in the cerebral hemorrhage the best amount of bleeding, the initial establishment of the diagnosis of cerebral hemorrhage can new clinical indicators, as the best Chinese medicine diagnosis and treatment of medical conservative lay the foundation for the research.Method: Cerebral hemorrhage on rat model of intervention is different from traditional Chinese medicine to the two analysises,first, neurological deficit scores, for observing changes in nerve function in rats; the secsond ,Detect NSE serum values by ELISA -box.Result: (1) Chinese medicine intervention cerebral hemorrhage model rats to bleeds around the stove the organization to have the treatment function. (2) After 1 days, neural function defect scoring in the same blood loss drug there is no difference between groups and model group (P>0.05), But higher than surgical group, there are significant differences (P<0.01). Administration groups and model group, its neural function defect score visible with the increase in the amount of bleeding and a rising trend. After 7 days after the operation, under the same amount of bleeding, drug delivery Group score is less than the model group (P<0.05), especially the 27ul drug delivery group, the most obvious. (3)After 7 days after surgery, serum level of NSE in rats, the model group, and delivery are higher than surgical group, and group effect of medication is better than the model group, especially 27ul significantly, serum NSE level is significantly lower (P<0.01). Group compared to a group of medication, 27ul, 41ul, 53ul, 67ul and serum NSE level compared to a very significant difference (P<0.01), its 41ul and 53ul, 67ul, statistically significant comparison (P<0.05), omparison, there was no significant difference between 67 and 53ul (P>0.05). (4) Analysis of serum NSE by ROC curve, serum NSE preliminary definition reflects the diagnosis of irreversible degree of brain damage after intracerebral hemorrhage range is 14.73ng/ml-19.99ng/ml. Conclusion: (1) Intervention of traditional Chinese medicine can significantly improve the neurologic symptoms in rats with intracerebral hemorrhage; regulation of serum level of NSE in rats after intracerebral hemorrhage. (2) Preliminary prompted the intervention of traditional Chinese medicine of traditional Chinese medicine in treatment of acute hemorrhagic apoplexy in 41ul (human 30mL) is an effective and safe. (3) Serum NSE levels can be used as sensitive indicators reflect the degree of brain damage after intracerebral hemorrhage and preliminary determination of serum NSE as irreversible brain damage after intracerebral hemorrhage the diagnosis value of 14.73ng/ml-19.99ng/ml.