Quality Of Life In Patients With Ulcerative Colitis And The Efficacy Of The Intervention With Chinese Medicine

Objectives:To investigate the quality of life in patients with ulcerative colitis and analyze factors related to it, we give them Chinese medicine sequential treatment and observe the clinical efficiency and its impact on quality of life,so as to improve the quality of life in patients with ulcerative colitis and provide the basis for countermeasures.Methods:Chinese IBDQ scale was used in the study,60 patients with IBDQ survey of patients with ulcerative colitis were randomly divided into treatment group and control group. The Treatment group was given oral QingchangHuashi decoction with herbs Enema retention therapy as active therapy, and then FuzhengQingchang decoction as maintain therpy;The control group was given with enteric-coated tablets of mesalazine (5-ASA) 4g/d for active action and then the dose was cut to 1.5g/d as maintaining therapy. The duration of the therapy was 24 weeks.Analysis the clinical efficiency and quality of life in patients at the end of the therapy.Results:The IBDQ score of the 60 ulcerative colitis patients in bowel, systemic, emotional and social dimensions were 47.92±9.188,22.00±5.082,57.15±10.669,22.95±6.256 respectively, and IBDQ total score was 150.02±27.464. Gradually Regression analysis showed that the factors related to quality of life were gender, occupation, residence and Sutherland DAI and symptoms. The total effective rate in treatment group and control group was of no statisticall significance(P>0.05); Clinical symptom score in treatment group was significantly lower than before treatment(P<0.01) when compared with control group, and there was statistical significance (P<0.05); Sutherland DAI score in treatment group was significantly lower than before treatment (P<0.01) when compared with control group; Intestinal mucosa colonoscopy and pathological score after treatment in treatment group were statistically lower than before treatment (P<0.01),but there were no statistical significance between the two groups(P>0.05);The mucosal healing rate of the two groups was not significant; There was significant difference on IBDQ scores than before treatment of the two groups(P<0.01), but there were no significant difference in terms of bowel,body,emotional dimentions and IBDQ total score of the two groups after treatment.Conclusions:Quality of life in patients with ulcerative colitis were imparied,and the factors including gender, occupation, residence and symptoms. The clinical efficiency of the treatment group was better than the control group,especially on terms of allieviating symptoms and improving quality of life in UC patients.