| Purpose:The subject of clinical effects to be adopted, evaluation of traditional Chinese medicine syndromes, liver enzymes, jaundice, weightChanges in abdominal girth decrease, liver fibrosis, and coagulation function were to observe the change in Modified wide-Yu Tang and western medicine treatment of ascites in liver cirrhosis the clinical efficacy, and further explore the pathogenesis of cirrhosis of the Liver and the benefits of water, the lineAir France wide initial control mechanism of liver cirrhosis, and patients to reduce pain and improve the clinical efficacy and prevention of other complications of decompensated cirrhosis appearance to provide ideas.Method:1.Random experiments:All eligible subjects were from the Chinese medicine hospital in Wuhan City, Hubei Province, out-patient and inpatient liver disease patients,74 patients were randomly as the width of the flavored soup of depression treatment group and western medicine combined with Western control group 37 cases. 2. Experimental drugs:Control group selected based therapies (oral furosemide, spironolactone tablets and intravenous infusion of drugs such as Liver JiangMei); the treatment group were based on the width of the additional service of depression soup flavored soups, daily one, each taking 200ml, morning and evening hours service; more than one drug for two weeks to two weeks for a course of treatment, general treatment effect 6 months after treatment statistics, and followed up six months to observe recurrence of ascites, abdominal circumference changes, weight changes and so on.3. OUTCOME MEASURES:Two groups before treatment of sex, age, course, license type, underlying diseases, clinical and other basic data points were compared by statistical analysis no significant difference (P> 0.05), that the two groups were comparable. According to the clinical efficacy of treatment, evaluation of traditional Chinese medicine syndromes, liver enzymes, jaundice, weight change, waist circumference reduction, liver fibrosis, and changes in coagulation function were assessed for statistical analysis to evaluate the effectiveness of drugs.4. Statistical analysis:End of the experiment were analyzed statistically using spss13.0 statistical analysis software.S of all data are measurement data, said test of significance using t test, count data using u test and x2 test.P<0.05 by the test will be considered the difference statistically significant.Results:1. Comparison of the overall effect:the treatment group healed in 15 cases, markedly effective in 15 cases,5 cases,2 cases, the total effective 94.58%; the control group healed in 6 cases, markedly effective in 8 cases,10 cases and ineffective in 13 cases, total effective rate of 64.86%, the Ridit test, P<0.01, significant effect that the treatment group than the control group.2. TCM syndromes comparison:two drugs on TCM syndrome in patients with liver cirrhosis the total effective rate, was statistically significant (P<0.05), prompt treatment group on improvement of clinical symptoms than the control group.3. The impact of aminotransferase:ALT treatment group improved compared with before treatment, was statistically significant (P<0.01); the control group improved transaminase before and after treatment, there are also significant differences (P<0.05); but the treatment grouptransaminase improved significantly better than the control group compared the value of the treatment group was statistically significant ALT (P<0.05).This conclusion illustrates the water treatment group, Shugan Lee, the line width in the gas regulating traditional Chinese medicine are to enhance the role of transaminase.4. Of jaundice:After treatment, total bilirubin, direct bilirubin, indirect bilirubin significantly improved compared with before treatment there was significant difference (P<0.01); control group after treatment bilirubinSu, direct bilirubin, indirect bilirubin improved significantly (P<0.05). The two groups, the treatment group's improvement in total bilirubin than the control group (P<0.05), that treatment group Shugan and Water, Qi in traditional Chinese medicine to improve width of total bilirubin, direct bilirubinSu, indirect bilirubin, improve circulation, prevent cirrhosis of the liver caused by compression of intrahepatic bile duct obstruction bile has a good effect.5. Coagulation comparison:After treatment, the PT, APTT, TT and other than those before treatment improved after treatment, self-comparison to improve significantly (P<0.01); control group improved significantly compared before and after their own (P<0.05); difference between the two groups before and after treatment were significant (P<0.05).6. Weight, abdominal circumference, ascites recurrence rate of change of comparison:the treatment group and control group after treatment than before treatment body weight and waist circumference significantly improved, but the comparison between the two groups, treatment group improved significantly better than control group patients,comparison of the two significant differences (P<0.05).Conclusion:Studies have shown that wide in the Modified Decoction of depression treatment of ascites due to cirrhosis Western therapies can significantly improve the TCM syndrome and improve liver function and other indicators, especially in patients with late recurrence of ascites, body weight and abdominal girth changes are more obvious effect, Clinical use of safe non-toxic and side effects and should be introduced. |
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