The Application Research Of Quantitative Temperature Testing At Glans Penis

Objective: To explore the application value of quantitative temperature testing (QTT) on forensic medicine identification, clinical diagnosis and treatment of neurogenic erectile dysfunction (nED) and premature ejaculation (PE).Methods: TSA-II thermal sensory analyzer was used to measure the threshold of cold, cold & pain, heat and heat & pain in 22 male with normal erectile and ejaculation function, 35 definite nED patients and 34 PE patients at dorsal glans (DG), left thenar (LT) and left thigh interior (LTI) under limits model, PE pateints were also divided into two groups: 12 severe PE patients and 22 mild PE patients based on their medical history and primary complain. Calculating relative sensory threshold of DG, which meaned the ratio between correspponding sensory threshold of DG and LT, DG and LTI as well. Applying independent sample t-test to analyze the differences between groups.Results: nED group showed no significant statistical differences (p>0.05) on cold and cold & pain when compared to the control group, no matter sensory threshold or relative threshold, illuminated that glans penis had low sensitivity to cold and cold & pain in both healthy male and nED patients. However, nED group had significant increase (p<0.05) on sensory threshold and relative threshold of heat and heat & pain at DG than the control group.Compared to the control group, PE patients showed significant increase (p<0.05) of heat & pain at LTI, and significant decrease (p<0.05) on relative threshold of heat & pain between DG and LTI. Nevertheless, we found no significant statistical changes (p>0.05) than the control group on sensory threshold of cold, cold & pain, heat, heat & pain at DG, and other relative threshold had no statistical differences (p>0.05) as well.Severe PE patients showed significant decreased (p<0.05) on sensory threshold and relative threshold of heat and heat & pain at DG, meanwhile other indicators had no statistical differences (p>0.05) than the control group. Mild PE patients, however, exhibited another condition. Heat and heat & pain threshold of DG and LTI was significantly higher (p<0.05) than the control group, and relative threshold of heat between DG and LT, DG and LTI was also significantly increased (p<0.05), while other indicators showed no significant differences (p>0.05).Conclusions:①QTT is an effective method to evaluate structure and function states of pudendal nerve, especially on small nerve fibers, which conduct temperature sense and pain. This technique could detect more effectually—when compared to traditional electrophysiological testing—on potential pathological changes of structure or functional disorder of pudendal nerve. It is more sensitive to find out pudendal nerve dysfunction. Therefore, QTT could be applied in clinical diagnosis and forensic medicine identification of nED.②QTT technique, as considered, could be utilized as accessory clinical diagnosis method of PE, and be one kind of objective evidence of selective penile dorsal nerve neurotomy. This diagnosis technique, nonetheless, requires more systemic research in details as a new type of practical technology.