Public Distribution Analysis And Coagulation Function Of Membrane Of Inferior Vena Cava Type For Clinic Features Of The Patients With Budd Chiarri Syndrome

[Objective]To study the clinic punlic distribution of Budd-Chiarri syndrome and coagulation ability of membrane obstruction of inferior vena cava type, so as to understand the development and pathogenesis mechanism and provide scientific basis for treatment and pathogenesis[Material and Methods]1. Cases collection:Collected all dependable clinic data of 1592 patients with Budd-Chiarri Syndrome who live in Shandong Province and came from many hospital, to divde four types hepatic small vein (HSV), hepatic main vein (HMV), inferior vena cava (IVC) and combine HMV and IVC according to their position, and made the descriptive analysis of data about ageing, sex, medical history and Clinical symptoms and signs.2. Coagulation function test:Collected 128 patients with membrane obstruction of IVC from Heze city hopital 78 and Shan county hospital 50 according to the image of ultrasound and angiography. Normal group people 100 cases came from physical examination in Heze city hospital, male 56 y, female 44y, age range 18-55y, average age 38.2, except cardiovascular disease, hypertension and diabetes. All cases took blood using Sodium citrate tube, PT, PT-INR, APTT, Fbg-time, Fbg-c, TT, AT-III:A and DD were Determined by Systmex-CA 7000 machine. All measurement finished in 4h.3. Statistical analysis:All data processed by the SAS 16.0.[Results]1. The cases are increased in the last decade years, more in adults,incidences in male and female are equal. The highest cases number is the IVC type(57.2%,911/1592), then CHI type (28.5%,454/1592), HMV type (13.4%,214/1592) and HSV type (0.8%,13/1592). The course of the HSV type is acute, the course of the HMV type is acute and chronic but more, the course of IVC type and CHI type are chronic. Cause of the HSV type is clear, Cause of the HMV type 19.6% is clear and related with coagulative abnormal, cause of IVC type and CHI type 90% are not clear.2. The numerical value of PT, PT-INR, Fbg-time, TT, APTT increased significantly and the the numerical value of Fbg-c decreased significantly in the experimental group comparing to the normal control group (Fbg-time P<0.05, the other blood coagulation indexes P<0.01).[Conclusions]1. The both types of IVC type and CHI type are main types and interesting with special clinic character and not clear cause in Shandong Province2. Thrombosis of blood coagulation disorder is not the main cause of inferior vena cava of Budd-Chiarri syndrome.