Study On Phthalates Detection In Food And The Characteristic Of Migration

Since it emerged that chemical substances from plastic food packaging might contaminate foods and endanger people’s long-term health, consideration of the possibility of migration of chernical substances from plastic food packaging materials into foodstuffs has been an important aspect of food safety that has attracted increasing attention. Phthalates are a group of plasticizers commonly used to make plastics more flexible in a variety of household and consumer products. Five kinds of phthalates, DMP, DEP, DBP, BBP and DEHP, that have adverse effects on human health were chosen for instrumental analysis and migration test in this paper. This study established a method of detection5phthalates by GC-MS and the pretreatment method of extraction phthalates from water and oil. The characteristic of phthalate migration from plastic packaging into water and oil was investigated under specific conditions.First of all, this study established a method of detection5phthalates by GC-MS obtained in SIM mode. And the instrument detection limit was5.6～15.8μg/L(S/N=3). A reliable method, based on solid-phase extraction (SPE) with C18adsorbent, was developed for determination and quantification of5phthalates in drinking water by gas chromatography-mass spectrometry. An enabled sequential extraction method, base on liquid-liquid extraction coupled with SPE, was established for determination and quantification of5phthalates in oil by GC-MS, with acetonitrile as eluent. Different brands of packaged drinking water and oil purchased from a local supermarket were detected. Secondly, the regulation of phthalate migration from PC and PET packaging to water and oil was investigated under specific conditions. The migration of DBP, used as a model, was selected to research the migration from PC and PET into water and oil. The results show that migration levels of DBP to water increase with time before reaching equilibrium and that migration levels and rates increase with storage temperature. Accelerated solvent extraction (ASE), coupled with GC-MS, was developed and successfully validated for the determination of the initial phthalate concentration in polymers PET and PC.Finally, predicted migrations were calculated using the initial concentrations of DBP in the polymers in a model, along with known variables such as temperature and exposure time. The diffusion coefficients (D) and partition coefficient (KP,F) were calculated from simple equations for the applied test conditions. Predicted results were higher than experimental values, as expected.