Effects Of Probiotic Preparation On Growth Performance And Immune Indices Of Weaner Piglets

This experiment was conducted to study the effects of probiotic preparation on growth performance,immune indexes, morphology, pH Valus and Volatile Fatty Acids of weaner piglets. Forty-eight crossed-bred (Duroc×Landrace×Yorkshine) piglets with an average weight of (6.39±0.42) kg were randomly assigned to2groups (control group and probiotic group) with4replicates in each group and6piglets with each pen balanced for sex, weight and litter origin. The piglets in the control group were fed a basal diet, and the others in the probiotic group were fed the basal diet supplemented with the probiotic preparation at a concentration of109CFU per kg feed. The feeding trial lasted for21days.The results are as folloes:1.The growth performance and immune system of weaned piglets were improved by dietary probiotic administration supplementation. The results showed that:Average daily gain(ADG)was increased(P<0.05),F/G was decreased significantly(P<0.05)and Diarrhea rates was also decreased significantly(P<0.05) for piglets fed with diet containing the probiotic administration.2) On day7, the serum IL-1(3of probiotic group was increased(P<0.05). On day21, the serum IgG, IL-6, TNF-a and lleum intestinal mucosa SIgA was increased significantly (P<0.05). Jejunum intestinal mucosa SIgA was increased,but not significantly (P>0.05). The IgA levels in feces, the percentage of CD3+,CD4+and CD8+, the ratio of CD4+/CD8+of T-lymphocyte was unaffected.2.The villus height, crypt depth, IELs and goblet cells of weaned piglets were improved by dietary probiotic administration supplementation. The results showed that:On day7, villus height and IELs of the probiotic group were significant longer than the control in jejunum and ileum(P<0.05). The ileal goblet cells of probiotic group was increased(P<0.05)and the ilea crypt depth of probiotic group was decreased significantly(P<0.05). On day14, probiotic significantly increased the length of villus height in jejunum and ileum(P<0.05).Addition with probiotic significantly improved IELs and decreased crypt depth in jejunum(P<0.05). On day21, villus height of the probiotic group were significant longer than the control in jejunum and ileum(P<0.05). Probiotic significantly increased IELs and goblet cells, decreased crypt depth in jejunum(P<0.05).3.Volatile Fatty Acids of weaned piglets were improved by dietary probiotic administration supplementation. The pH valus in ileum of probiotic group was was reduced. The aim of this was to investigate the effect of Probiotic Administration on pH Valus and Volatile Fatty Acids in Weaned Piglets. The results showed that:The pH valus in ileum of probiotic group was were lower (P<0.05) comparing with control group on7day. The rest of the time, the ilea pH valus of probiotic group was decreased,but not significantly(P>0.05). All in all, the pH valus of the probiotic group were lower than the control about0.10-0.57unit. Butyric acid and lactic acid in cecum of probiotic group were increased (P<0.05) comparing with control group on7day. Acetic acid and propionic acid of probiotic group were also increased,but not significantly(P>0.05). Probiotic significantly increased VFA and lactic acid concentration in cecum on14and21day.