| Background"Prehypertension" refers to systolic blood pressure (SBP) for the120-139mmHg (1mm Hg=0.133calf) and (or)80-89mmHg in diastolic blood pressure (DBF), namely from the normal, blood pressure to the diagnosis of hypertension, the transition phase. By the American hypertension prevention, diagnosis, evaluation, and treatment of the Joint Committee on the7th report (referred JNC7), May21,2003JNC7first proposed [1]. Blood pressure in patients within the range of120~139/80to89mmHg, the risk of hypertension, blood pressure in the lower levels of those times; until1.85/115mm Hg in the full range of blood pressure from115/75mmHg, for each additional20/10mm Hg blood pressure, cardiovascular risk is increased by1times the risk of hypertension25years after the age of55with normal blood pressure rate of90%[2,3]. Our studies have shown that in1991,2002,2007, pre-hypertension accounted for33.8%,61.5%and54.6%[5]. China’s Beijing Fuwai, Ahn Jung Hospital Epidemiology2006survey showed that China’s population of prehypertension was38.9%-41.3%, normal blood pressure in the prehypertensive population after10years the proportion of hypertension were22.2%and52.6%[6], which is the former times. Thus, a large number of prehypertensive population is progress in a very important source of clinical hypertensive patients. A large number of studies have shown that pre-hypertension, patients have been merged multiple cardiovascular risk factors such as dvslipidemia, glucose, obesity, etc., and cause microalbuminuria, decreased small artery compliance, left ventricular structural abnormalities and cardiac hypertrophy, and crown increased risk of heart disease, cerebrovascular events. The current treatment for prehypertension, the main non-drug treatment-based, the JNC7guidelines recommend lifestyle modifications to prevent cardiovascular disease, drug therapy is still not a lot of evidence based medicine, so to explore Chinese medicine treatment of prehypertension, delay the progress hypertension, target organ is a feasible way. In this study, retrospective case-analysis The prehypertension symptom distribution characteristics to provide more objective evidence for the TCM treatment of prehypertension.PurposeCases forward-looking, cross-sectional study, survey the prehypertensive the TCM symptom distribution characteristics, provide a more objective basis for TCM treatment of prehypertension.MethodThe merger of major diseases such as cancer patients with prehypertension in the Guangdong Provincial Hospital inpatient and outpatient screening a total of315cases, collected from a survey of the age, height, weight, diet and living habits, medical history, family history, combined with cardiac vascular risk factors and other basic information, and collection of patients with the four diagnostic information, refer to "Traditional Chinese Drug Guidelines for clinical research (Zheng Xiaoyu, editor) of the second series of" Traditional Chinese Drug Treatment of Hypertension Guidelines for clinical research and the China Press of Traditional Chinese Medicine published in Chinese medical science "Vertigo TCM type of liver yang, yin, liver and kidney, obstructing phlegm, blood stasis, such as five types of descriptive statistics; and data collection entry excel database, and import SPSS17.0statistical analysis, traditional Chinese medicine syndrome of Screening using hierarchical cluster analysis of the k-clustering method, and to draw evidence-based indicators of the four major categories of syndromes, and summarize the prehypertension The TCM syndromes.Result(l)The prehypertension syndromes, including the resistance card in the phlegm, blood stasis, Liver Yang Ascending Syndrome, yin and yang deficiency of both. In prehypertensive patients with signs and symptoms integral "Vertigo" and "chest tightness","eat less","vomiting phlegm, the highest proportion.3clinical baseline data, male patients significantly higher age of onset is mainly concentrated in the30-50year-old high body mass index can not be an accurate count of diet history, smoking history, history of alcohol consumption was significantly higher, past medical history and cardiovascular risk factors, dyslipidemia was51.43%,18.41%incidence of hyperuricemia, diabetes/glucose metabolism were detected in11.75%, the occurrence of cardiovascular target organ damage to incidence of impaired cardiac structure ’’function10.48%, renal dysfunction,7.94%, cerebrovascular disease was6.03%,12.38%of peripheral vascular disease, retinal arteriosclerosis1.59%. ConclusionThe prehypertension TCM syndromes including phlegm retention syndrome, blood stasis, Liver Yang Ascending Syndrome, yin and yang deficiency of both, in which phlegm, blood stasis is the major syndromes of prehypertension performance.(2) symptoms in patients with prehypertension,"Vertigo","chest tightness","eat less","vomiting phlegm" Chinese medicine symptom elements may be pre-hypertension, suggesting that the phlegm may be in the prehypertension as the main disease machine(3) age of onset is mainly concentrated in the30-50years of age and younger tendencies. Overweight/obesity is an important cause of the incidence of prehypertension progression to an important cause of high blood pressure prehypertension with cardiovascular risk factors, the body may start the regulatory function, suggesting that attention to prehypertension to prevent, delay prehypertension progress... |
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